Results 11 to 20 of about 79,032 (289)

Anesthetic drug midazolam inhibits cardiac human ether-à-go-go-related gene channels: mode of action

Drug Design, Development and Therapy, 2015
Nadine Vonderlin,1 Fathima Fischer,1 Edgar Zitron,1,2 Claudia Seyler,1 Daniel Scherer,1 Dierk Thomas,1,2 Hugo A Katus,1,2 Eberhard P Scholz1 1Department of Internal Medicine III, University Hospital Heidelberg, 2German Centre for Cardiovascular ...
Vonderlin N, Fischer F, Zitron E, Seyler C, Scherer D, Thomas D, Katus HA, Scholz EP,   +7 more
doaj   +1 more source

Comparison of Oral Midazolam With Intravenous Midazolam for Sedation Children During Upper Gastrointestinal Endoscopy

Acta Medica Iranica, 2016
Upper endoscopy is a common procedure for the diagnosis and treatment of upper digestive tract diseases. The increasing number of pediatric gastrointestinal procedures has led to increasing attention on the safety and efficacy of medications used for ...
Ahmad Khodadad, Majid Aflatoonian, Rozita Jalilian, Nazanin Babaei, Farzaneh Motamed, Alireza Ebrahime Soltani, Behnaz Rasoolzadeh, Fatemeh Motavasselian, Nima Rezaei   +8 more
doaj   +1 more source

Use of advanced intravenous conscious sedation techniques in complex oral surgery procedures: Comparison of midazolam, midazolam-propofol and midazolam-propofol-alfentanil combinations [PDF]

, 2021
Aim: This retrospective observational study evaluates the safety and efficacy of intravenous sedation using midazolam only or combinations of two or three drugs including propofol and alfentanil for complex dental surgery such as implant placement or ...
Kingsford, NM, Mather, CI, Offord, DJ, Paterson, R, Robb, ND   +4 more
core   +2 more sources

Efficacy of remimazolam versus midazolam for procedural sedation: post hoc integrated analyses of three phase 3 clinical trials

Endoscopy International Open, 2022
Background and study aims Remimazolam is an ultra-short acting, fast onset/fast offset benzodiazepine for intravenous use in procedural sedation, general anesthesia, and Intensive Care Unit sedation.
Van-Anh Dao, Frank Schippers, Thomas Stöhr   +2 more
doaj   +1 more source

Avoiding the incompatibility of peripheral parenteral nutrition solution and midazolam injection for intravenous sedation

Fujita Medical Journal, 2021
Objectives: We have observed white turbidity when a midazolam injection is administered from a lateral tube during the administration of a peripheral parenteral nutrition (PPN) solution. The aim of the current study was to determine how to avoid compound
Akihiko Futamura, Takashi Higashiguchi, Takeshi Chihara, Yuka Yokota, Yoshinori Itani   +4 more
doaj   +1 more source

Perbedaan Waktu Pulih Sadar Anestesi Umum Sevofluran dengan Premedikasi Midazolam dan tanpa Premedikasi Midazolam

Jurnal Anestesi Perioperatif, 2022
Pemberian premedikasi midazolam memberikan efek sedasi yang panjang sehingga menimbulkan pulih sadar yang lebih lama. Tujuan penelitian ini adalah mengetahui perbedaan waktu pulih sadar anestesi umum sevofluran dengan dan tanpa premedikasi midazolam ...
Purwoko Purwoko, Ardana Tri Arianto, Djoko Tjahyo Nugroho   +2 more
doaj   +1 more source

Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically ill children: An observational, prospective, controlled study

Pharmacology Research & Perspectives, 2022
Altered physiology caused by critical illness may change midazolam pharmacokinetics and thereby result in adverse reactions and outcomes in this vulnerable patient population.
Bikalpa Neupane, Hitesh Pandya, Tej Pandya, Rupert Austin, Neil Spooner, James Rudge, Hussain Mulla   +6 more
doaj   +1 more source

The effect of midazolam dose and age on the paradoxical midazolam reaction in Korean pediatric patients [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundAlthough midazolam administration may occasionally induce a paradoxical episode, such as threatened crying and violent behavior in children, systematic studies on the causes of paradoxical reaction are limited.
Young Hee Shin, Myung Hee Kim, Jung Jin Lee, Soo Joo Choi, Mi Sook Gwak, Ae Ryoung Lee, Mi Na Park, Hyo Sung Joo, Jung Hee Choi   +8 more
doaj   +1 more source

Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium?

PLoS ONE, 2022
Midazolam is a widely used short-acting benzodiazepine. However, midazolam is also criticized for its deliriogenic potential. Since delirium is associated with a malfunction of the neurotransmitter acetylcholine, midazolam appears to interfere with its ...
Katharina Rump, Caroline Holtkamp, Lars Bergmann, Hartmuth Nowak, Matthias Unterberg, Jennifer Orlowski, Patrick Thon, Zainab Bazzi, Maha Bazzi, Michael Adamzik, Björn Koos, Tim Rahmel   +11 more
doaj   +1 more source

USE OF MIDAZOLAM IN PAEDIATRIC DENTISTRY

, 2023
Introduction and aim: Midazolam is a short-acting, effective sedative with a rapid onset and minimal side effects, belonging to the benzodiazepine group.
P Poláčková, J Vašáková, E Dokoupilová   +2 more
core   +1 more source