Results 21 to 30 of about 79,032 (289)
Midazolam impedes lung carcinoma cell proliferation and migration via EGFR/MEK/ERK signaling pathway
Open Medicine, 2023 Non-small-cell lung cancer (NSCLC) is a dominating type of lung cancer with high morbidity and mortality. Midazolam has been reported to promote cell apoptosis in NSCLC, but the molecular mechanism of midazolam remains to be further explored.
Zhang Xiangchao +3 more
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Transmucosal nasal drug delivery : systemic bioavailability of nasally applied midazolam [PDF]
, 2008 Transmucosal nasal drug delivery is a drug delivery option for challenging clinical situations where common drug administrations (e.g., intravenous, intramuscular, or oral) are inapplicable.
Suter-Zimmermann, Katja
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Frontiers in Psychiatry, 2023 IntroductionThe aim of the present study was to investigate the behavioral effects of the benzodiazepine midazolam in male mice, in models of anxiolysis, learning, and abuse-related effects.MethodsIn a first set of experiments, male Swiss mice were ...
Caio Jovita-Farias +14 more
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Prescription drug forms with midazolam [PDF]
Farmacja Polska, 2021 Midazolam is a benzodiazepine derivative. It is characterized by a short half-life. It has a strong sedative, anxiolytic and hypnotic effect. It also acts as an anticonvulsant and relaxes skeletal muscles.
Anna Czech, Renata Jachowicz
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Scientific Reports, 2017 The benzodiazepine midazolam is widely used in critical care medicine. Midazolam has a clinically active metabolite, 1-hydroxymidazolam. The contribution of 1-hydroxymidazolam to the effects of midazolam is controversial. The aim of the current study was
Monika Balk +4 more
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Midazolam alleviates cellular senescence in SH‐SY5Y neuronal cells in Alzheimer's disease
Brain and Behavior, 2023 Background Alzheimer's disease (AD) impacts the daily life of aging people. Oligomerized amyloid β (Aβ)‐associated neuronal senescence is involved in the pathological mechanism of AD.
Ping Wang +4 more
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Clinical Pharmacology of Midazolam in Neonates and Children: Effect of Disease—A Review
International Journal of Pediatrics, 2014 Midazolam is a benzodiazepine with rapid onset of action and short duration of effect. In healthy neonates the half-life (t1/2) and the clearance (Cl) are 3.3-fold longer and 3.7-fold smaller, respectively, than in adults. The volume of distribution (Vd)
Gian Maria Pacifici
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Comparison of nasal Midazolam with Ketamine versus nasal Midazolam as a premedication in children
Saudi Journal of Anaesthesia, 2014 Background: T his study was done to compare effects of intranasal midazolam and intranasal midazolam with ketamine for premedication of children aged 1-12 yrs undergoing intermediate and major surgeries.
Sonal S Khatavkar, Rochana G Bakhshi
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Perioperative Medicine, 2022 Background Sedative premedication with benzodiazepines has been linked with prolonged recovery and inadequate emergence during the immediate postoperative period.
Karin Stuff +9 more
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Effects of midazolam on acquisition and extinction of conditioned taste aversion memory in rats. [PDF]
, 2009 Some intravenous anesthetic agents such as midazolam are known to induce anterograde and retrograde amnesia. We analyzed the effect of midazolam by the conditioned taste aversion (CTA) acquisition and retention.
Yoshida, Harushi +5 more
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