Results 181 to 190 of about 122,656 (259)

Hox Gene Variation Drives Morphological Specialization of Humpback Grouper Cromileptes altivelis

Integrative Zoology, EarlyView.
Cromileptes altivelis exhibits a distinctive “sunken head and humpback” morphology, formed through cranial remodeling. Genetic analyses identified unique amino acid variants in Hoxa7a and Hoxa10b, with functional tests confirming their role in enhancing osteoblast activity and driving cranial remodeling.
Xiaoying Cao, Zhaowei Zhong, Lisheng Wu, Quanyin Liu, Shaoxiong Ding   +4 more
wiley   +1 more source

Three consecutive cases of rhinocerebral mucormycosis in calves caused by Lichtheimia ramosa infection on a beef cattle farm. [PDF]

J Vet Med Sci
Kazama C, Kato C, Kawauchi K, Ito M, Hanafusa Y, Mikami O.   +5 more
europepmc   +1 more source

Chromatin Accessibility Profiling of the Canine Brain Reveals Regulatory Programs Associated With Dog‐Wolf Divergence and Human Psychiatric Risk

Integrative Zoology, EarlyView.
The dog is a valuable model for studying social behavior and neuropsychiatric disease. We generated an ATAC‐seq atlas of 7 brain regions and pituitary from 4 beagles, identifying 251,492 CREs. Integrating dog‐wolf divergence revealed tissue‐specific CREs overlapping divergent loci, including neuronal and neuroendocrine genes.
Biao Deng, Junze Wu, Ye Liu, Xuan Li, Yuanfang Xu, Rongjie Duan, Yibo Tong, Jinsheng Xu, Mengyang Ni, Zijie Scott Zhang, Dan Xue, Bowen Zhou, Yanhu Liu, Rui Cheng, Yuedong Zhang, Ya‐Ping Zhang   +15 more
wiley   +1 more source

Functional ultrasound imaging reveals early pathway-specific reorganization of central visual circuits in a mouse model of Batten disease. [PDF]

Neurobiol Dis
Yin F, Ding Y, Chang H, Prifti V, Feng J, Freedman EG, Foxe JJ, Doyley M, Wang KH.   +8 more
europepmc   +1 more source

Association of enlarged perivascular space burden with silent cerebral infarcts in children with sickle cell disease

British Journal of Haematology, EarlyView.
Enlarged perivascular spaces (ePVS) in the basal ganglia and centrum semiovale are highly prevalent in children with sickle cell disease (SCD). Enlarged PVS in the basal ganglia are associated with the presence of silent cerebral infarcts, another marker of neurological disease, in children with SCD. Summary Children with sickle cell disease (SCD) have
Kristine A. Karkoska, Jahnavi Gollamudi, Brady J. Williamson, Russell P. Sawyer, Daniel Woo, Achala Vagal, Hyacinth I. Hyacinth   +6 more
wiley   +1 more source

Diagnostic value of multi-regional multi-parameter transcranial sonography in differentiating Parkinson's disease from essential tremor. [PDF]

Front Neurol
Yao H, Wang W, Hu C, Liang X, Zhang L.
europepmc   +1 more source

Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions

Brain Pathology, EarlyView.
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich, David S. Priemer, Charles Harker Rhodes, Daniel P. Perl, Kurenai Tanji, James E. Goldman   +5 more
wiley   +1 more source

Advanced Eye Movement Features Measured by Quantitative Oculography as Candidate Biomarkers for Progressive Supranuclear Palsy. [PDF]

Diagnostics (Basel)
Ouyang H, Liu B, Peng Q, Ma Z, Tang Z, Chang A, Liu M, Cao X, Xu Y, Xia Y.   +9 more
europepmc   +1 more source

α‐Synuclein strain homogeneity in multiple system atrophy subtypes

Brain Pathology, EarlyView.
Two different subtypes of multiple system atrophy are recognized: MSA‐C and MSA‐P. In this manuscript, Lau et al. investigate whether MSA‐C and MSA‐P are caused by different strains of α‐synuclein aggregates. By performing conformational fingerprinting experiments as well as in vitro and in vivo seeding assays, their findings suggest that both MSA‐C ...
Heather H. C. Lau, Nicholas R. G. Silver, Surabhi Mehra, Raphaella W. L. So, Le yao Li, Alison Mao, Erica Stuart, Cian Schmitt‐Ulms, Bradley T. Hyman, Martin Ingelsson, Joel C. Watts   +10 more
wiley   +1 more source

Nuclear Speckle Protein SRRM2 Co-localized with Pathological Tau (pTauS396) in Neuronal and Glial Cells in Progressive Supranuclear Palsy. [PDF]

Acta Histochem Cytochem
Nazar FH, Arrozi AP, Kato T, Yanagisawa D, Itoh Y, Tooyama I, Bellier JP.   +6 more
europepmc   +1 more source