Results 51 to 60 of about 5,104,116 (389)

Burnout among healthcare providers in the complex environment of the Middle East: a systematic review

open access: yesBMC Public Health, 2019
Burnout is a syndrome characterized by emotional exhaustion, increased depersonalization, and a diminished sense of personal accomplishment due to chronic emotional stress at work.
Z. Chemali   +7 more
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

The Generalization of Inflectional and Derivational Patterns to Novel Stems by L1 Turkish Learners of L2 English

open access: yesDilbilim Araştırmaları Dergisi, 2019
Studies investigating the morphological processing of affixed forms have to date focused predominantly on inflectional rather than derivational forms and have mostly tested L1 speakers.
Esra Ataman   +2 more
doaj   +1 more source

A Possible Submarine Landslide and Associated Tsunami at the Northwest Nile Delta, Mediterranean Sea [PDF]

open access: yesOceanography, 2014
A hypothetical landslide tsunami at the Nile Delta in the Eastern Mediterranean Sea is modeled in order to study hazards it would pose to the region. The methodology used is based on numerical simulation of the generation and propagation of a realistic ...
Ahmet Yalciner   +6 more
doaj   +1 more source

The Middle East Justice & Reconciliation Initiative [PDF]

open access: yes, 2007
Report on Muslim/Christian faith-based reconciliation dialogue in Cyprus - this report includes a description of faith-based reconciliation methodology in relation to The Middle East Justice & Reconciliation ...
Brian Cox
core  

Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus

open access: yesFrontiers in Microbiology, 2019
Middle East respiratory syndrome (MERS) is a deadly viral respiratory disease caused by MERS-coronavirus (MERS-CoV) infection. To date, there is no specific treatment proven effective against this viral disease.
Chean Yeah Yong   +4 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Middle East respiratory syndrome coronavirus (MERS-CoV)

open access: yesSaudi Medical Journal, 2017
Coronavirus memiliki famili besar yang menyebabkan penyakit pada manusia dan hewan. Pada manusia dapat menyebabkan penyakit dengan gejala mulai dari common cold sampai Severe Acute Respiratory Syndrome (SARS)
D. Murniati
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Middle East respiratory syndrome coronavirus (MERS-CoV): A review.

open access: yesGERMS, 2019
As a novel coronavirus first reported by Saudi Arabia in 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) is responsible for an acute human respiratory syndrome.
N. Ramadan, H. Shaib
semanticscholar   +1 more source

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