Results 51 to 60 of about 2,985,063 (347)
Frontiers in Endocrinology, 2019 Objective: To evaluate intraday serum progesterone levels on the day of final oocyte maturation in women undergoing ovarian stimulation in a GnRH-antagonist protocol.Study design, size, and duration: The study was done as a prospective observational ...
Upma Shanker +9 more
doaj +1 more source
A Possible Submarine Landslide and Associated Tsunami at the Northwest Nile Delta, Mediterranean Sea [PDF]
Oceanography, 2014 A hypothetical landslide tsunami at the Nile Delta in the Eastern Mediterranean Sea is modeled in order to study hazards it would pose to the region. The methodology used is based on numerical simulation of the generation and propagation of a realistic ...
Ahmet Yalciner +6 more
doaj +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Chaos from massive deformations of Yang-Mills matrix models
Journal of High Energy Physics, 2020 We focus on an SU(N ) Yang-Mills gauge theory in 0 + 1-dimensions with the same matrix content as the bosonic part of the BFSS matrix model, but with mass deformation terms breaking the global SO(9) symmetry of the latter to SO(5) × SO(3) × ℤ2 ...
K. Başkan +3 more
doaj +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci +6 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus
Frontiers in Microbiology, 2019 Middle East respiratory syndrome (MERS) is a deadly viral respiratory disease caused by MERS-coronavirus (MERS-CoV) infection. To date, there is no specific treatment proven effective against this viral disease.
Chean Yeah Yong +4 more
semanticscholar +1 more source
Health in the Middle East [PDF]
BMJ, 2006 At the height of the Arab-Islamic civilisation between the 8th and 12th century, scholars laid the foundation for modern medicine based on observation and reasoning.1 Avicenna's Al Qanun of Medicine was the standard medical text in Europe for several centuries. In the bimaristans (hospitals), still standing in the heart of Aleppo (figure), the mentally
openaire +3 more sources