Results 71 to 80 of about 57,763 (248)

Comparison of Serologic Assays for Middle East Respiratory Syndrome Coronavirus [PDF]

Emerging Infectious Diseases, 2019
Middle East respiratory syndrome coronavirus (MERS-CoV) was detected in humans in 2012. Since then, sporadic outbreaks with primary transmission through dromedary camels to humans and outbreaks in healthcare settings have shown that MERS-CoV continues to pose a threat to human health.
Harvey, Ruth, Mattiuzzo, Giada, Hassall, Mark, Sieberg, Andrea, Müller, Marcel A., Drosten, Christian, Rigsby, Peter, Caly, L., Li, C., Zhao, L., Tan, W., Peiris, M., Perera, M., Kang, C., Wang, J. S., Haagmans, B., Okba, N. M.A., Gopal, R., Myhill, S., Thornburg, N.   +19 more
openaire   +6 more sources

Synergies in Self‐Assembly—From Supramolecular Polymers to Defined Hierarchical Superstructures

Journal of Polymer Science, EarlyView.
Shaping supramolecular polymers built from molecular building blocks into superstructures with defined dimensions. Synergies within supramolecular architectures such as chirality or an additional second orthogonal driving force that does not interfere with the central supramolecular motif facilitate the confinement of the growth of these ...
Klaus Kreger, Florian Behrendt, Johannes C. Brendel   +2 more
wiley   +1 more source

Review on development of potential inhibitors of SARS-CoV-2 main protease (MPro)

Future Journal of Pharmaceutical Sciences, 2022
Background The etiological agent for the coronavirus illness outbreak in 2019–2020 is a novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (COVID-19), whereas coronavirus disease pandemic of 2019 (COVID-19) has ...
Soumya Gulab Katre, Alpana Jagdish Asnani, Kumar Pratyush, Nilima Gangadhar Sakharkar, Ashwini Gajanan Bhope, Kanchan Tekram Sawarkar, Vaibhav Santosh Nimbekar   +6 more
doaj   +1 more source

Viral Shedding and Antibody Response in 37 Patients With Middle East Respiratory Syndrome Coronavirus Infection

Clinical Infectious Diseases, 2015
In a study of viral load, shedding, and immune response in 37 cases of Middle East respiratory syndrome coronavirus infection, virus was not eliminated upon development of neutralizing serum antibodies.
V. Corman, A. Albarrak, A. Omrani, M. Albarrak, M. Farah, Malak M. Almasri, D. Muth, Andrea Sieberg, B. Meyer, A. Assiri, T. Binger, K. Steinhagen, E. Lattwein, J. Al-Tawfiq, M. Müller, C. Drosten, Z. Memish   +16 more
semanticscholar   +1 more source

Role of the DPP4 Receptor in SARS‐CoV Entry: Insights From Docking and Molecular Dynamics Simulations

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein–receptor interactions play a critical role in viral entry and pathogenesis. While ACE2 is the primary receptor for SARS‐CoV, the role of DPP4 as potential coreceptor remains underexplored. This study investigates the binding mechanisms and dissociation dynamics of the SARS‐CoV/DPP4, SARS‐CoV/ACE2 and MERS‐CoV/DPP4 complexes using ...
Patrícia Pereira Duzi Carvalho, Nelson Augusto Alves   +1 more
wiley   +1 more source

MERS Coronavirus: An Emerging Zoonotic Virus

Viruses, 2019
Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging virus that was first reported in humans in June 2012 [...]
Fang Li, Lanying Du
doaj   +1 more source

[Middle East Respiratory Syndrome Coronavirus (MERS-CoV) – Camel virus and zoonotic pathogen]

Berliner und Münchener Tierärztliche Wochenschrift, 2021
The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) has been firstly identified in September 2012 as causative agent of severe and lethal respiratory disease in humans (Table 1).
Christian Meyer zu Natrup, Asisa Volz
doaj   +1 more source

Acute myocarditis associated with novel Middle East respiratory syndrome coronavirus

Annals of Saudi Medicine, 2016
The novel Middle East respiratory syndrome coronavirus (MERS-CoV) has been identified as a cause of pneumonia; however, it has not been reported as a cause of acute myocarditis. A 60-year-old man presented with pneumonia and congestive heart failure.
T. Alhogbani
semanticscholar   +1 more source

Rapid and Sensitive Detection of RNA Viruses through Imaging of Marker Molecules Derived from Designed Circular DNA Probes

Small Methods, EarlyView.
This study presents a rapid and sensitive virus detection method that employs imaging of virus‐specific DNA markers. Utilizing specially designed single‐stranded circular DNA probes, this method captures RNA fragments from RNase‐digested viral genomes during the reverse transcriptase‐based reaction, resulting in double‐stranded markers that are ...
Yoon‐ha Jang, Taesoo Kim, Su‐jin Hong, Se‐yeon Kim, Hyeseung Hwang, Siwon Kim, Su‐a Kang, Nabin Won, Dogeun Kim, Min Jae Kim, Yong Pil Chong, Seongsoo Jang, Kyubong Jo, Kwang‐il Lim   +13 more
wiley   +1 more source

Type I interferon signalling and interferon‐responsive microglia in health and disease

The FEBS Journal, EarlyView.
Recent insights reveal that type I interferon (IFN‐I) signalling plays critical roles in the nervous system beyond antiviral defence. Dysregulated IFN‐I activity is increasingly linked to neurological dysfunction and neurodegeneration, with microglia as central mediators. This review explores the broader impact of IFN‐I signalling on the nervous system
Jose P. Lopez‐Atalaya, Aysha M. Bhojwani‐Cabrera   +1 more
wiley   +1 more source