Results 181 to 190 of about 6,907 (199)
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Urology, 2007
To develop a novel therapeutic strategy against human bladder cancer using Ad-MK-E1a-a midkine (MK) promoter-regulated, conditionally replicating, adenovirus.We tested several human cancer cell lines in vitro, including those of bladder cancer (KK47, 5637, and T24), lung cancer (A549), and head and neck cancer (H891).
Shuji, Terao +11 more
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To develop a novel therapeutic strategy against human bladder cancer using Ad-MK-E1a-a midkine (MK) promoter-regulated, conditionally replicating, adenovirus.We tested several human cancer cell lines in vitro, including those of bladder cancer (KK47, 5637, and T24), lung cancer (A549), and head and neck cancer (H891).
Shuji, Terao +11 more
openaire +2 more sources
Rheumatoid Arthritis and Midkine
2012Midkine (MK) is expressed in synovial tissues of patients with rheumatoid arthritis, and MK concentration are elevated in synovial fluid and serum of the vast majority of patients with the disease. Serum MK levels might aid the diagnosis of rheumatoid arthritis, since 71.9% of patients that test negative for rheumatoid factor exhibited elevated levels.
Hisako Muramatsu +2 more
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Expression of midkine in the cochlea
Hearing Research, 2001Midkine (MK) is one of a new family of heparin-binding growth factors involved in the regulation of growth and differentiation. We have analyzed expression of MK in the cochlea using ICR mice within 1 day from birth. The expression of MK in the cochlea was confirmed by Western blotting and immunohistochemistry.
X Q, Jia +3 more
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Antibody Characterization Report for Midkine
2021A peer-reviewed antibody characterization article corresponding to this Zenodo preprint is openly available at F1000Research: https://doi.org/10.12688/f1000research.130587.1 This report presents a guide to selecting high-quality commercial antibodies against Moesin by immunoblot (Western blot), immunoprecipitation, and immunofluorescence Midkine by ...
Ayoubi, Riham +2 more
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Midkine Expression in Human Periapical Granulomas
Journal of Endodontics, 2011The expression of midkine (MK), a heparin-binding growth factor, is increased in various human tumors, making it a promising tumor marker and target for tumor therapy. MK is also related to the regulation of the development and etiology of chronic or autoimmune diseases; however, the involvement of MK in apical periodontitis has never been examined ...
Keisuke, Hatori +4 more
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Midkine in Skeletal Physiology
2012In the adult skeleton bone remodeling, the continuous turnover of bone matrix and mineral by bone resorption and bone formation, needs to be in balance to maintain bone mass. This balance is ensured by the coordinated activities of osteoclasts (bone-resorbing cells) and osteoblasts (bone-forming cells), which are regulated by numerous factors ...
Astrid Liedert +3 more
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2012
Midkine (MK) is expressed in embryonic stem (ES) cells and neural precursor cells including neural stem cells, and promotes their growth and survival. Because of the strong expression of MK in neural precursor cells, the role of MK in these cells has been clarified by analyzing cells derived from MK-deficient embryos.
Hisako Muramatsu +2 more
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Midkine (MK) is expressed in embryonic stem (ES) cells and neural precursor cells including neural stem cells, and promotes their growth and survival. Because of the strong expression of MK in neural precursor cells, the role of MK in these cells has been clarified by analyzing cells derived from MK-deficient embryos.
Hisako Muramatsu +2 more
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2012
The molecular mechanisms of midkine (MK) in myocardial damage and the possibility of clinical application of MK for heart failure were assessed. In the acute phase of cardiac ischemia/reperfusion (I/R) injury of mice, MK showed an anti-apoptotic reaction for cardiomyocytes through Bcl-2 and ERK activation.
Mitsuru Horiba, Kenji Kadomatsu
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The molecular mechanisms of midkine (MK) in myocardial damage and the possibility of clinical application of MK for heart failure were assessed. In the acute phase of cardiac ischemia/reperfusion (I/R) injury of mice, MK showed an anti-apoptotic reaction for cardiomyocytes through Bcl-2 and ERK activation.
Mitsuru Horiba, Kenji Kadomatsu
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2012
Midkine, a heparin-binding growth factor, promotes the growth, survival, and migration of various cell populations, and it is over-expressed in many malignant human tumors. Midkine expression is generally increased in colon carcinomas compared to normal colon tissue. Additionally, colon adenomas with medium-to severe-dysplasia exhibit increased midkine
Özgür Kemik +2 more
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Midkine, a heparin-binding growth factor, promotes the growth, survival, and migration of various cell populations, and it is over-expressed in many malignant human tumors. Midkine expression is generally increased in colon carcinomas compared to normal colon tissue. Additionally, colon adenomas with medium-to severe-dysplasia exhibit increased midkine
Özgür Kemik +2 more
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Vascular Restenosis and Midkine
2012Cardiovascular diseases are a burden on the healthcare and economy of developed countries, because they are among the leading causes of morbidity and mortality. Percutaneous coronary intervention, including stenting, is now an established treatment for coronary artery disease.
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