Results 181 to 190 of about 6,987 (195)
Some of the next articles are maybe not open access.
Midkine Expression in Human Periapical Granulomas
Journal of Endodontics, 2011The expression of midkine (MK), a heparin-binding growth factor, is increased in various human tumors, making it a promising tumor marker and target for tumor therapy. MK is also related to the regulation of the development and etiology of chronic or autoimmune diseases; however, the involvement of MK in apical periodontitis has never been examined ...
Keisuke, Hatori +4 more
openaire +2 more sources
Midkine in Skeletal Physiology
2012In the adult skeleton bone remodeling, the continuous turnover of bone matrix and mineral by bone resorption and bone formation, needs to be in balance to maintain bone mass. This balance is ensured by the coordinated activities of osteoclasts (bone-resorbing cells) and osteoblasts (bone-forming cells), which are regulated by numerous factors ...
Astrid Liedert +3 more
openaire +1 more source
2012
Midkine (MK) is expressed in embryonic stem (ES) cells and neural precursor cells including neural stem cells, and promotes their growth and survival. Because of the strong expression of MK in neural precursor cells, the role of MK in these cells has been clarified by analyzing cells derived from MK-deficient embryos.
Hisako Muramatsu +2 more
openaire +1 more source
Midkine (MK) is expressed in embryonic stem (ES) cells and neural precursor cells including neural stem cells, and promotes their growth and survival. Because of the strong expression of MK in neural precursor cells, the role of MK in these cells has been clarified by analyzing cells derived from MK-deficient embryos.
Hisako Muramatsu +2 more
openaire +1 more source
2012
The molecular mechanisms of midkine (MK) in myocardial damage and the possibility of clinical application of MK for heart failure were assessed. In the acute phase of cardiac ischemia/reperfusion (I/R) injury of mice, MK showed an anti-apoptotic reaction for cardiomyocytes through Bcl-2 and ERK activation.
Mitsuru Horiba, Kenji Kadomatsu
openaire +1 more source
The molecular mechanisms of midkine (MK) in myocardial damage and the possibility of clinical application of MK for heart failure were assessed. In the acute phase of cardiac ischemia/reperfusion (I/R) injury of mice, MK showed an anti-apoptotic reaction for cardiomyocytes through Bcl-2 and ERK activation.
Mitsuru Horiba, Kenji Kadomatsu
openaire +1 more source
2012
Midkine, a heparin-binding growth factor, promotes the growth, survival, and migration of various cell populations, and it is over-expressed in many malignant human tumors. Midkine expression is generally increased in colon carcinomas compared to normal colon tissue. Additionally, colon adenomas with medium-to severe-dysplasia exhibit increased midkine
Özgür Kemik +2 more
openaire +1 more source
Midkine, a heparin-binding growth factor, promotes the growth, survival, and migration of various cell populations, and it is over-expressed in many malignant human tumors. Midkine expression is generally increased in colon carcinomas compared to normal colon tissue. Additionally, colon adenomas with medium-to severe-dysplasia exhibit increased midkine
Özgür Kemik +2 more
openaire +1 more source
Vascular Restenosis and Midkine
2012Cardiovascular diseases are a burden on the healthcare and economy of developed countries, because they are among the leading causes of morbidity and mortality. Percutaneous coronary intervention, including stenting, is now an established treatment for coronary artery disease.
openaire +1 more source
General Information on Midkine
2012Midkine (MK) is a heparin-binding cytokine or growth factor and promotes survival, growth, migration, gene expression and other activities of target cells. MK is rich in both basic amino acids and cysteine and has about 50% sequence identity with pleiotrophin (PTN).
openaire +1 more source
2012
Prostate cancer is the most common malignancy in the developed countries. Midkine is expressed in prostate cancer but not in normal prostate, indicating that midkine can be used as a biomarker for diagnosis of prostate cancer. The levels of midkine expression are higher in the late stage and metastatic prostate tumors compared to the early stage ...
openaire +1 more source
Prostate cancer is the most common malignancy in the developed countries. Midkine is expressed in prostate cancer but not in normal prostate, indicating that midkine can be used as a biomarker for diagnosis of prostate cancer. The levels of midkine expression are higher in the late stage and metastatic prostate tumors compared to the early stage ...
openaire +1 more source
Midkine Expression in Ameloblastomas
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2012openaire +1 more source