Use of oral midodrine for weaning off norepinephrine in patients with septic shock
Background Early administration of norepinephrine in septic shock patients is linked to better survival rates. However, vasopressor dependence often occurs during the recovery phase, delaying ICU discharge. Objectives A comparative study was conducted on
Mohamed Obaya +3 more
doaj +2 more sources
Idiopathic orthostatic hypotension, midodrine, and anaesthesia [PDF]
A patient with idiopathic orthostatic hypotension receiving chronic oral midodrine therapy required anaesthesia for coronary artery bypass grafting. A perioperative infusion of phenylephrine was substituted for midodrine, an alpha-2 agonist, enabling hypotension resulting from low systemic vascular resistance to be controlled easily.
P. J. Osborne, L. W. Lee
openalex +5 more sources
Control, Fludrocortisone or Midodrine for the treatment of Orthostatic Hypotension (CONFORM-OH): results from an internal pilot randomised controlled trial. [PDF]
Mossop H +14 more
europepmc +5 more sources
Haematological toxicity of midodrine in haemodialysis patients [PDF]
Hassane Izzedine +4 more
openalex +4 more sources
Failure of pacemaker therapy in a pediatric patient with neurally mediated complete heart block and syncope: A case report [PDF]
Key Clinical Message Neurally mediated syncope (NMS) is a well‐known condition that can be subdivided into three subgroups: vasopressor type, cardioinhibitory type, and mixed type. While different degrees of sinus bradycardia occur at the time of syncope
Mohammad Dalili, Feisal Rahimpoor
doaj +2 more sources
Utility of an alpha-1 adrenergic agonist in the management of chylothorax: a case series and management algorithm [PDF]
Chylothorax is the accumulation of lymphatic fluid (chyle) within the pleural space. There are multiple causes, including traumatic and non-traumatic mechanisms.
Ruben Peralta +5 more
doaj +2 more sources
Challenges in the Treatment of Hepatorenal Syndrome-Acute Kidney Injury: A US Chart Review of Treatment Patterns and Survival Outcomes. [PDF]
ABSTRACT Background Treatments for hepatorenal syndrome with acute kidney injury (HRS‐AKI) that are not FDA‐approved have been widely used in the United States (US) with variable outcomes. This study describes the practice patterns, outcomes, and healthcare utilization around vasopressor use before terlipressin approval in 2022. Methods A retrospective
Sanyal AJ +12 more
europepmc +2 more sources
Midodrine initiation criteria, dose titration, and adverse effects when administered to treat shock: A systematic review and semi-quantitative analysis. [PDF]
Puissant MM +7 more
europepmc +2 more sources
Midodrine Efficacy in Orthostatic Hypotension [PDF]
To the Editors—We recently came across the review article by Parsaik et al. “Midodrine for Orthostatic Hypotension: A Systematic Review and Meta-Analysis of Clinical Trials” (J Gen Intern Med 28(11): 1496–503), and feel obligated to comment on several deficiencies of this work.
Robert D. Fealey +6 more
openaire +7 more sources
Oral Midodrine as an Adjunct to Accelerate Vasopressor Liberation in Septic Shock: A Prospective Randomized Controlled Trial [PDF]
ANAS V +5 more
europepmc +2 more sources

