Results 31 to 40 of about 3,700 (182)

Impact of Midodrine on Optimization of β-blocker Therapy in Patients with Heart Failure with Reduced Ejection Fraction [PDF]

, 2023
Introduction: Midodrine, an α-adrenergic agonist approved for orthostatic hypotension, is used off-label for hypotension in patients with heart failure with reduced ejection fraction (HFrEF). However, its prevalence, clinical outcomes, and risks in HFrEF
Ruiz, Maria A, Falli, Maura, Martinez, Dayana, de Almeida, Kristen, Gopalani, Radhan B   +4 more
core   +1 more source

Value of Midodrine in Management of Refractory ascites due to liver cirrhosis [PDF]

Zagazig University Medical Journal
Background: Patients with ascites, hepatorenal syndrome, or both who have reduced plasma renin activity can benefit from midodrine, which is an α1-adrenergic agonist, by increasing the effective arterial blood volume by splanchnic vasoconstriction and ...
Hanan Abo Alela, Abeer Abdelkader, Amira Soliman, Taghrid Abdalla, Shaimaa Awwaad   +4 more
doaj   +1 more source

Potential risks in using midodrine for persistent hypotension after cardiac surgery: a comparative cohort study

Annals of Intensive Care, 2020
Background Persistent hypotension is a frequent complication after cardiac surgery with cardiopulmonary bypass (CPB). Midodrine, an orally administered alpha agonist, could potentially reduce intravenous vasopressor use and accelerate ICU discharge of ...
Jan-Alexis Tremblay, Philippe Laramée, Yoan Lamarche, André Denault, William Beaubien-Souligny, Anne-Julie Frenette, Loay Kontar, Karim Serri, Emmanuel Charbonney   +8 more
doaj   +1 more source

Continuation of Midodrine Upon ICU Discharge [PDF]

, 2020
Indications for Continuation of Alpha-1 Agonist Midodrine Upon ICU Discharge Hussain, Fahad, MSII; Rao, Deepti, MD Introduction: Persistent hypotension in patients affected by circulatory shock is a common barrier to discharge in the ICU.
Rao, Deepti S, Hussain, Fahad
core  

Hyponatremia in Cirrhosis: Clinical Outcomes and Comparative Analysis of Different Treatment Approaches [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Hyponatremia is a common electrolyte disturbance in cirrhotic patients, resulting from impaired renal water excretion due to elevated levels of Antidiuretic Hormone (ADH) and is strongly associated with morbidity and mortality.
Kranthi Dandi, Debabrata Banerjee, Amol S Dahale, Abhijeet S Karad, Yogesh S Bade   +4 more
doaj   +1 more source

Predicting Therapeutic Efficacy of Pharmacological Treatments in Children with Postural Orthostatic Tachycardia Syndrome: A Mini-Review

Children, 2023
Postural orthostatic tachycardia syndrome (POTS) is common in children, with an excessive increment in heart rate when moving from the supine to upright position. It has significant negative impacts on the daily life of pediatric patients.
Siying Fan, Yaxi Cui, Ying Liao, Hongfang Jin   +3 more
doaj   +1 more source

Clinical Prognostic Factors in Pediatric Patients With Orthostatic Intolerance

Global Pediatric Health, 2020
Midodrine is widely used for orthostatic intolerance (OI); however, little is known about the prognostic factors of OI after midodrine treatment. We retrospectively reviewed electronic medical charts to investigate clinical prognostic factors of OI on ...
Kazue Ishitsuka MD, MPH, PhD, Kaori Yamawaki MD, Miwako Horikawa MD, Hisaya Nakadate MD, PhD, Akira Nagai MD, PhD, Akira Ishiguro MD, PhD   +5 more
doaj   +1 more source

Treatment of prolonged clonidine-induced autonomic instability with midodrine: a case report about a new approach or a cautionary tale?

Emergency and Critical Care Medicine, 2023
. Background. Clonidine is a centrally acting α2 adrenergic and imidazoline-1 receptor agonist that can cause somnolence, bradycardia, and hypotension within several hours of ingestion.
Saada Malouf, Catherine Henry, Lara Pemberton, Joe-Anthony Rotella   +3 more
doaj   +1 more source

The effect of fludrocortisone and midodrine on ambulatory blood pressure biomarkers and symptoms of syncope

Blood Pressure
Introduction Fludrocortisone and midodrine are frequently used to raise blood pressure (BP) in patients with vasovagal syncope (VVS)/low BP phenotype and orthostatic hypotension (OH), despite limited supporting evidence.
Kate Doyle, Ciara P. Rice, Rose Anne Kenny, Robert Briggs, Amanda H. Lavan   +4 more
doaj   +1 more source

The Impact of Midodrine On Guideline-Directed Medical Therapy in Patients Admitted with Systolic Heart Failure.

, 2023
BACKGROUND: Midodrine is occasionally used off-label to treat hypotension associated with advanced heart failure. Its association with changes in prescription of guideline-directed medical therapy (GDMT) is unknown.
Cohen, Adam J, Scoma, Christopher B, Eichelberger, Gerry, Fernandez, Joel, Lee, Dae Hyun, Money, David, Usmani, Ahsan   +6 more
core   +1 more source