Results 21 to 30 of about 3,700 (182)

Role of Midodrine on Vasopressor Duration in Patients with Sepsis [PDF]

, 2023
Existing literature evaluating the off-label use of midodrine has focused primarily on postoperative hypotensive patients requiring a single vasopressor.
Draper, Heather M, Combs, Jenna L, Belfer, Julie J, Ellena, Kamah J   +3 more
core   +1 more source

Stimulation of Alpha-1-Adrenergic Receptor Ameliorates Obesity-Induced Cataracts by Activating Glycolysis and Inhibiting Cataract-Inducing Factors [PDF]

Endocrinology and Metabolism, 2022
Background Obesity, the prevalence of which is increasing due to the lack of exercise and increased consumption of Westernized diets, induces various complications, including ophthalmic diseases. For example, obesity is involved in the onset of cataracts.
Yong-Jik Lee, Yoo-Na Jang, Hyun-Min Kim, Yoon-Mi Han, Hong Seog Seo, Youngsub Eom, Jong-suk Song, Ji Hoon Jeong, Tae Woo Jung   +8 more
doaj   +1 more source

The Use of Midodrine as an Adjunctive Therapy to Liberate Patients from Intravenous Vasopressors: A Systematic Review and Meta-analysis of Randomized Controlled Studies

Cardiology and Therapy, 2023
Background Studies evaluating the role of midodrine as an adjunctive therapy to liberate patients with shock from intravenous (IV) vasopressors have yielded mixed results.
Mohamed Hamed, Sheref A. Elseidy, Ahmed Elkheshen, Jamal Maher, Adel Elmoghrabi, Ahmed Zaghloul, Andrew Panakos, Sidakpal Panaich, Marwan Saad, Ayman Elbadawi   +9 more
doaj   +1 more source

Calcitonin gene-related peptide predicts therapeutic response to midodrine hydrochloride in children with vasovagal syncope

Frontiers in Neuroscience, 2022
The vasoconstriction agent midodrine hydrochloride is a vital treatment for pediatric patients diagnosed with vasovagal syncope (VVS), although the efficacy is variable.
Lintian Li, Huacai Zhao, Xiuxiu Ma, Fuyong Jiao, Jing Lin   +4 more
doaj   +1 more source

Oral Midodrine Administration During the First 24 Hours of Sepsis to Reduce the Need of Vasoactive Agents: Placebo-Controlled Feasibility Clinical Trial

Critical Care Explorations, 2021
Objectives:. Our preliminary data and observational studies suggested an increasing “off label” use of oral midodrine as a vasopressor sparing agent in various groups of critically ill patients, including those with sepsis.
Amos Lal, MBBS, FACP, Vrinda Trivedi, MBBS, Mahrukh S. Rizvi, MD, Amy Amsbaugh, RRT, LRT, Melissa K Myers, MD, Khaled Saleh, MD, Rahul Kashyap, MBBS, MBA, Ognjen Gajic, MD, MSc, FCCP, FCCM   +7 more
doaj   +1 more source

Norepinephrine is More Effective Than Midodrine/Octreotide in Patients With Hepatorenal Syndrome-Acute Kidney Injury: A Randomized Controlled Trial

Frontiers in Pharmacology, 2021
Background: Terlipressin is the first-line pharmacological treatment for hepatorenal syndrome. When terlipressin is unavailable, midodrine/octreotide or norepinephrine, with albumin, represent the alternative treatments. The comparative efficacy of these
Eman Ibrahim El-Desoki Mahmoud, Doaa H Abdelaziz, Doaa H Abdelaziz, Sherief Abd-Elsalam, Noha O. Mansour   +4 more
doaj   +1 more source

Effect of Oral Vasopressors Used for Liberation from Intravenous Vasopressors in Intensive Care Unit Patients Recovering from Spinal Shock: A Randomized Controlled Trial

Critical Care Research and Practice, 2022
Background. Early vasopressor utilization has been associated with improved outcomes of patients with spinal shock; however, there are difficulties in weaning off vasopressors, in which patients after recovery from spinal shock develop a state of ...
Ahmed Talaat Ahmed Ali, Mervat Anwar Abd EL-Aziz, Ahmed Mohamed Abdelhafez, Amr Mohamed Ahmed Thabet   +3 more
doaj   +1 more source

Urine electrolytes guide treatment of Gitelman syndrome and recurrent syncope-A case report. [PDF]

Physiol Rep
Abstract Syncope is a common reason for inpatient admission. Few case studies describe an association between syncope and Gitelman syndrome (GS). Herein, we present a case of a woman with hypokalemia and recurrent syncope which eventually led to a diagnosis of GS. A physiologic approach to urine electrolyte interpretation informed clinical decisions to
Agrawal S, Fifer KM, Farouk SS, Rein JL.
europepmc   +2 more sources

Long-Term Albumin Therapy in Cirrhosis With Ascites: Not an Answer yet. [PDF]

United European Gastroenterol J
United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
Juanola A, Ginès P.
europepmc   +2 more sources

Pharmacokinetic parameters and haemodynamic actions of midodrine in young volunteers [PDF]

, 1993
In two groups of volunteers pharmacological parameters of the antihypotensive drug midodrine have been investigated. The first group of 12 male healthy volunteers received 2.5 mg midodrine hydrochloride intravenously, as drinking solution or as tablet ...
Grobecker, H. F., Kees, Frieder K.
core   +1 more source