Oral midodrine for prophylaxis against post-spinal anesthesia hypotension during hip arthroplasty in elderly population: a randomized controlled trial [PDF]
BMC AnesthesiologyBackground We aimed to evaluate the efficacy of midodrine as a prophylaxis against post-spinal hypotension in elderly patients undergoing hip arthroplasty.
Sarah Amin +7 more
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Comparison of the effect of midodrine versus octreotide on hemodynamic status in cirrhotic patients with ascites [PDF]
Journal of Research in Medical Sciences, 2011 Background: In cirrhotic patients peripheral vasodilatation may decrease renal blood flow and subsequently raises plasma renin activity. Octreotide with several mechanisms causes peripheral arterial vasoconstriction.
Mohammad Minakari +3 more
doaj +1 more source
Role of Midodrine on Vasopressor Duration in Patients with Sepsis [PDF]
, 2023 Existing literature evaluating the off-label use of midodrine has focused primarily on postoperative hypotensive patients requiring a single vasopressor.
Draper, Heather M +3 more
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Midodrine-Induced Nightmares in the Treatment of Orthostatic Hypotension: A Case Report. [PDF]
, 2023 Click on the Resource Link to access the article (may not be free).Midodrine was the first medication approved by the Food and Drug Administration (FDA) for the treatment of orthostatic hypotension.
Brodeur, Michael, Tran, Lara*
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Stimulation of Alpha-1-Adrenergic Receptor Ameliorates Obesity-Induced Cataracts by Activating Glycolysis and Inhibiting Cataract-Inducing Factors [PDF]
Endocrinology and Metabolism, 2022 Background Obesity, the prevalence of which is increasing due to the lack of exercise and increased consumption of Westernized diets, induces various complications, including ophthalmic diseases. For example, obesity is involved in the onset of cataracts.
Yong-Jik Lee +8 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Background: Terlipressin is the first-line pharmacological treatment for hepatorenal syndrome. When terlipressin is unavailable, midodrine/octreotide or norepinephrine, with albumin, represent the alternative treatments. The comparative efficacy of these
Eman Ibrahim El-Desoki Mahmoud +4 more
doaj +1 more source
Impact of Midodrine on Optimization of β-blocker Therapy in Patients with Heart Failure with Reduced Ejection Fraction [PDF]
, 2023 Introduction: Midodrine, an α-adrenergic agonist approved for orthostatic hypotension, is used off-label for hypotension in patients with heart failure with reduced ejection fraction (HFrEF). However, its prevalence, clinical outcomes, and risks in HFrEF
Ruiz, Maria A +4 more
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Transcatheter Aortic Valve Replacement Outcomes in End-Stage Renal Disease Patients on Hemodialysis Requiring Midodrine [PDF]
, 2023 BACKGROUND: Patients with dialysis-dependent end-stage renal disease (ESRD) taking midodrine may be at high risk for poor outcomes following transcatheter aortic valve replacement (TAVR).
Daniel Spoon +21 more
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Annals of Intensive Care, 2020 Background Persistent hypotension is a frequent complication after cardiac surgery with cardiopulmonary bypass (CPB). Midodrine, an orally administered alpha agonist, could potentially reduce intravenous vasopressor use and accelerate ICU discharge of ...
Jan-Alexis Tremblay +8 more
doaj +1 more source
Pharmacokinetic parameters and haemodynamic actions of midodrine in young volunteers [PDF]
, 1993 In two groups of volunteers pharmacological parameters of the antihypotensive drug midodrine have been investigated. The first group of 12 male healthy volunteers received 2.5 mg midodrine hydrochloride intravenously, as drinking solution or as tablet ...
Grobecker, H. F., Kees, Frieder K.
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