Results 51 to 60 of about 5,599 (219)

Impact of Midodrine on Optimization of β-blocker Therapy in Patients with Heart Failure with Reduced Ejection Fraction [PDF]

, 2023
Introduction: Midodrine, an α-adrenergic agonist approved for orthostatic hypotension, is used off-label for hypotension in patients with heart failure with reduced ejection fraction (HFrEF). However, its prevalence, clinical outcomes, and risks in HFrEF
de Almeida, Kristen, Falli, Maura, Gopalani, Radhan B, Martinez, Dayana, Ruiz, Maria A   +4 more
core   +2 more sources

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

Rapidly Progressive Multiple System Atrophy—Cerebellar Type in a 52‐Year‐Old Woman: Diagnostic Challenges in a Resource‐Limited Setting

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Multiple system atrophy (MSA) is a progressive adult‐onset neurodegenerative disorder that manifests as a variable combination of cerebellar, parkinsonian, and autonomic dysfunctions. We report a case of a 52‐year‐old woman who presented with rapidly progressive gait ataxia, dysarthria, orthostatic hypotension, and urinary urgency.
Khushi V. Singh, Sai Priya Nimmagadda, Ameesh Panda, Rarigela Rohith, Tirth J. Patel, Sonika Gopathoti, Prajesh V. Patel, Mihirkumar P. Parmar, Saleh Mohammed   +8 more
wiley   +1 more source

Reversal of hepatorenal syndrome type 1 with terlipressin plus albumin vs. placebo plus albumin in a pooled analysis of the OT-0401 and REVERSE randomised clinical studies [PDF]

, 2017
Background The goal of hepatorenal syndrome type 1 (HRS-1) treatment is to improve renal function. Terlipressin, a synthetic vasopressin analogue, is a systemic vasoconstrictor used for the treatment of HRS-1, where it is available.
Araya, V., Boyer, T. D., Escalante, S., Frederick, R. T., Jamil, K., Pappas, S. C., Reddy, K. R., Rossaro, L., Sanyal, A. J., Teuber, P., Vargas, H. E., Wong, F.   +11 more
core   +2 more sources

Progress of non‐motor symptoms in early‐onset Parkinson's disease

Ibrain, Volume 11, Issue 4, Page 422-438, Winter 2025.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang, Aidi Luo, Shusheng Liao, Mei Liu, Jun Zhang, Zucai Xu   +5 more
wiley   +1 more source

Anti-hypotensive effect of “Yahom Navakot” in rats with orthostatic hypotension

Journal of Traditional and Complementary Medicine, 2022
Background and aim: Yahom Navakot (YN), is a Thai traditional medicine, consisting of 54 plants, for treating fainting and dizziness. Thus, YN might relieve orthostatic hypotension (OH) symptoms, but its therapeutic action is unclear.
Anjaree Inchan, Thanika Pathomwichaiwat, Tippaporn Bualeong, Sasipong Tipratchadaporn, Krongkarn Chootip   +4 more
doaj   +1 more source

Sleep Architecture Alterations Following High‐Dose Steroid Pulse Therapy: A Pilot Study Using a Portable Electroencephalogram‐Based Device

Neuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.
High‐dose steroid pulse therapy markedly reduces total sleep time, REM, and NREM sleep, as objectively demonstrated for the first time using a portable EEG‐based device. ABSTRACT Background Sleep disturbance is a common side effect of high‐dose steroid pulse therapy (SPT).
Hiroki Endo, Yuki Shigetsura, Misaki Chahara, Keisuke Kido, Etsuro Nakanishi, Sakiho Ueda, Kimitoshi Kimura, Akira Kuzuya, Hirotsugu Kawashima, Riki Matsumoto, Masahiro Tsuda, Shunsaku Nakagawa, Tomohiro Terada   +12 more
wiley   +1 more source

Reflex syncope: Diagnosis and treatment

, 2017
For the diagnosis of reflex syncope, diligent history-building with the patient and a witness is required. In the Emergency Department (ED), the assessment of syncope is a challenge which may be addressed by an ED Observation Unit or by a referral to a ...
Sutton, R
core   +2 more sources

A Young Female Who Develops Tachycardia and Orthostatic Intolerance Following a Recent Infection [PDF]

, 2013
Case Presentation The patient is a 20-year-old female with a history of asthma and anxiety with panic attacks who presented with palpitations and lightheadedness/pre-syncope. The morning of admission, she was attending a seminar and experienced an acute
Valentino, MD, PhD, Michael A.
core   +2 more sources

Role of Midodrine on Vasopressor Duration in Patients with Sepsis [PDF]

, 2023
Existing literature evaluating the off-label use of midodrine has focused primarily on postoperative hypotensive patients requiring a single vasopressor.
Belfer, Julie J, Combs, Jenna L, Draper, Heather M, Ellena, Kamah J   +3 more
core   +2 more sources