Results 111 to 120 of about 17,319 (251)
ObjectiveA bioequivalence (BE) study was performed to evaluate the pharmacokinetics, safety, and bioequivalence of two formulations of mifepristone tablets in healthy Chinese volunteers under fasting conditions.MethodsA single-center, open, randomized ...
Yufeng Yan +9 more
doaj +1 more source
Discovery of non-steroidal mifepristone mimetics:pyrazoline-based PR antagonists
Mifepristone is a non-selective antagonist of 3-oxosteroid receptors with both abortifacient and anti-endometriotic activities. Non-steroidal mimetics of mifepristone and progesterone are important templates for modulation of the progesterone receptor ...
Gray, David W.; id_orcid +9 more
core +1 more source
What is the impact of contraceptive methods and mixes of contraceptive methods on contraceptive prevalence, unmet need for family planning, and unwanted and unintended pregnancies? [PDF]
Background - In many low-and middle-income countries, there is high maternal, infant and child mortality due in part to low contraceptive use and high unmet need for family planning.
Ogollah, Reuben +13 more
core
Asoprisnil as a Novel Ligand Interacting with Stress-Associated Glucocorticoid Receptor
Background/objective: The glucocorticoid receptor (GR) is critical in regulating cortisol production during stress. This makes it a key target for treating conditions associated with hypothalamic–pituitary–adrenal (HPA) axis dysregulation, such as mental
Ovinuchi Ejiohuo +3 more
doaj +1 more source
Resetting the Stress System with a Mifepristone Challenge
Psychotic depression is characterized by elevated circulating cortisol, and high daily doses of the glucocorticoid/progesterone antagonist mifepristone for 1 week are required for significant improvement.
Dalm, S. +4 more
core +1 more source
Mifepristone-Inducible Caspase-1 Expression in Mouse Embryonic Stem Cells Eliminates Tumor Formation but Spares Differentiated Cells In Vitro and In Vivo [PDF]
Yi Wang +6 more
openalex +1 more source

