Results 91 to 100 of about 29,702 (243)

Selection, counterselection, and conditional gene expression for genetic biocontrol of insects

open access: yesInsect Science, Volume 33, Issue 2, Page 724-743, April 2026.
Selection, counterselection, and conditional expression can be used for sex separation. Selection (S) and counterselection (CS) genes are linked to the sex chromosomes (e.g., the X and Y chromosomes) to confer sex‐specific selection or counterselection based on the presence or absence of the S or CS genes.
Melanie Hempel, Zhijian Tu
wiley   +1 more source

Development of specific glucocorticoid receptor antagonists

open access: yesEuropean Journal of Psychotraumatology, 2012
Background / Methods : Mifepristone, a potent glucocorticoid receptor (GR) and progesterone receptor (PR) antagonist, has recently become the first medication approved for the treatment of Cushing's syndrome, the archetypal illness of cortisol ...
Joseph K. Belanoff
doaj   +1 more source

Oxycodone alleviates mifepristone‐stimulated human endometrial stromal cell injury by activating the Keap1/Nrf2/HO‐1 signaling pathway

open access: yesImmunity, Inflammation and Disease, 2023
Background Endometrial injury is a common disease in women caused by intrauterine inflammation, infections, and endocrine disorders. Human endometrial stromal cells (hEndoSCs) can maintain endometrial homeostasis and play an important role in repairing ...
Aibing Zhu, Fei Yao, Mingkun Shen
doaj   +1 more source

A pilot study on the use of letrozole with either misoprostol or mifepristone for termination of pregnancy up to 63 days [PDF]

open access: yes, 2011
Background: Letrozole is a third-generation selective aromatase inhibitor. Animal data suggested that it might be useful in medical abortion. We performed two pilot studies to assess the feasibility of using letrozole in combination with either ...
Ho, PC   +4 more
core   +1 more source

A Cluster of Three snoRNAs Including Jouvence Required in the Gut Determines Lifespan and Confers Neuroprotection Through Metabolic Parameters

open access: yesAging Cell, Volume 25, Issue 4, April 2026.
The disruption of a cluster of three snoRNAs in the epithelium of the gut deregulates the lipid and sterol (including the cholesterol) homeostasis. At the whole‐organism level, this chronic deregulation, all along life, decreases lifespan and leads to neurodegenerative lesions in old flies.
Sara Al Issa   +4 more
wiley   +1 more source

Feasibility of assessing the safety and effectiveness of menstrual regulation medications purchased from pharmacies in Bangladesh: a prospective cohort study. [PDF]

open access: yes, 2017
OBJECTIVE: To assess the feasibility of following up women who purchase mifepristone+misoprostol or misoprostol-only from pharmacies in order to measure the safety and effectiveness of self-administration of menstrual regulation.
Church, Kathryn   +6 more
core   +1 more source

Medication Management of Early Pregnancy Loss in an Urban Texas Emergency Department

open access: yesAcademic Emergency Medicine, Volume 33, Issue 4, April 2026.
ABSTRACT Background Among patients with early pregnancy loss (EPL) without medical complications or need for urgent surgical evacuation, treatment should largely be guided by patient preference. However, evidence describing medication management for EPL in the emergency department (ED) setting is limited.
Lindsay Cline   +6 more
wiley   +1 more source

Liberty and Property in the Patent Law [PDF]

open access: yes, 2002
Patents have seldom troubled civil libertarians. A specialized form of property, patents seemed pertinent to the technologies of traditional industry but little else.
Thomas, John R.
core   +1 more source

Use of point‐of‐care ultrasound in the diagnosis of uterine rupture

open access: yes
Ultrasound in Obstetrics &Gynecology, EarlyView.
S. Tartaglia   +5 more
wiley   +1 more source

NR3C1 Modulates Wnt Signalling to Influence the Invasiveness and Immune Features of Nonfunctioning Invasive Pituitary Adenomas

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Pituitary adenomas (PAs) are common intracranial tumours, and invasiveness in nonfunctioning invasive pituitary adenomas (NIPAs) predicts poor prognosis. The molecular mechanisms driving this phenotype remain unclear. This study explored the role of nuclear receptor subfamily 3 group C member 1 (NR3C1) in NIPA invasiveness and its regulation ...
Xiaoping Wang   +6 more
wiley   +1 more source

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