Results 81 to 90 of about 17,319 (251)

Oxycodone alleviates mifepristone‐stimulated human endometrial stromal cell injury by activating the Keap1/Nrf2/HO‐1 signaling pathway

open access: yesImmunity, Inflammation and Disease, 2023
Background Endometrial injury is a common disease in women caused by intrauterine inflammation, infections, and endocrine disorders. Human endometrial stromal cells (hEndoSCs) can maintain endometrial homeostasis and play an important role in repairing ...
Aibing Zhu, Fei Yao, Mingkun Shen
doaj   +1 more source

Spatial Disparities in Mifepristone Use for Early Miscarriage and Induced Abortion Among Obstetrician–Gynecologists Practicing in Massachusetts

open access: yesWomen's Health Reports
Background: About 25% of pregnancies end in early miscarriage or abortion annually in the United States. While mifepristone is part of the most effective medication regimen for miscarriage and abortion, regulatory burdens and legal restrictions limit its
Emily Newton-Hoe   +4 more
doaj   +1 more source

Experiences and Perceptions of Doctors, Nurses, and Midwives Providing Abortion Care in Australia: A Scoping Review

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 3, June 2026.
ABSTRACT Background Doctors, nurses, and midwives are key providers of abortion care for women in Australia. Providing abortion care is a challenging, contentious, and sometimes perilous occupation. Recent changes in the Australian abortion care landscape mean that it is essential to consider the experiences and perceptions of the abortion workforce ...
Katie Edmondson   +3 more
wiley   +1 more source

ALTERNATIVE APPROACHES TO MEDICAL ABORTION [PDF]

open access: yesTrakia Journal of Sciences
Medical abortion involving various pharmacological agents has demonstrated high levels of complete uterine evacuation. Alternative approaches involving letrozole, mifepristone, methotrexate used synergically with misoprostol are non-invasive elective ...
K. Telbiyska, M. Angelova
doaj   +1 more source

Mifepristone as a Potential Therapy to Reduce Angiogenesis and P-Glycoprotein Associated With Glioblastoma Resistance to Temozolomide

open access: yesFrontiers in Oncology, 2020
Glioblastoma, the most common primary central nervous system tumor, is characterized by extensive vascular neoformation and an area of necrosis generated by rapid proliferation.
Monserrat Llaguno-Munive   +7 more
doaj   +1 more source

Synergistic RU486 and olaparib therapy enhances apoptosis in endometriosis by simultaneously targeting hormonal signalling and DNA repair

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 11, Page 2947-2968, June 2026.
Background and Purpose Endometriosis is a chronic, hormone‐dependent disorder characterized by ectopic implantation of endometrial tissue, often accompanied by pain and infertility. Although the progesterone receptor modulator RU486 is effective for pain relief, its impact on lesion regression is limited, possibly due to apoptosis resistance and ...
Yujie Peng   +10 more
wiley   +1 more source

Reproductive outcomes following surgical removal of uterine fibroids

open access: yesМедицинский совет, 2019
The cohort prospective comparative study investigated the efficacy of mifepristone use in patients after surgical treatment of uterine myoma. It was shown that the use of mifepristone at a dose of 50 mg/day in a continuous mode for 3 months after ...
A. E. Mitichkin   +7 more
doaj   +1 more source

Predicting Response to Pro‐Cognitive Interventions in Mood Disorders: A Systematic Review by the International Society for Bipolar Disorders Targeting Cognition Task Force

open access: yesActa Psychiatrica Scandinavica, Volume 153, Issue 5, Page 374-401, May 2026.
ABSTRACT Introduction Major depressive disorder (MDD) and bipolar disorder (BD) are often associated with persistent cognitive deficits that impair psychosocial functioning. While pro‐cognitive interventions show promise, trial findings are inconsistent, potentially due to baseline factors influencing treatment response.
Dimosthenis Tsapekos   +30 more
wiley   +1 more source

Randomised preference trial of medical versus surgical termination of pregnancy less than 14 weeks' gestation

open access: yes, 2009
Objectives: To determine the acceptability, efficacy and costs of medical termination of pregnancy (MTOP) compared with surgical termination of pregnancy (STOP) at less than 14 weeks’ gestation, and to understand women’s decision-making processes and ...
Kelly, T.   +18 more
core   +1 more source

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