Results 71 to 80 of about 17,319 (251)
Photochemistry and Photobiology, EarlyView.Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson +5 more
wiley +1 more source
Journal of Mid-Life Health, 2018 Background: Leiomyomata causing symptoms have a deleterious effect on the health of women during reproductive age. Mifepristone, a progesterone antagonist was studied for reduction of symptoms in leiomyomata in perimenopausal women. Material and Methods:
Deepti Jain
doaj +1 more source
Journal of Family Medicine and Primary Care, 2023 Introduction: Misoprostol is widely used in the medical management of missed abortions. However, pretreatment with Mifepristone has shown to be effective but still not recommended to be used in missed abortions.
Nidhi Gupta +4 more
doaj +1 more source
Mifepristone occupies the coactivator protein space.
, 2013 A. ancSR2–progesterone–mifepristone (protein, slate blue; mifepristone, magenta) was overlaid with ancestral corticoid receptor–deoxycorticosterone–hSHP NRBox1 (PDB accession code: 2Q3Y) complex.
Jennifer K. Colucci (119487) +1 more
core +1 more source
Trends in Non‐Resident Abortion Rates in Illinois From 2001–2018
Perspectives on Sexual and Reproductive Health, EarlyView.ABSTRACT Objective To describe trends in resident and non‐resident abortion rates in Illinois between 2001 and 2018. Methods Using Illinois Department of Public Health data, we calculated the resident abortion rate (abortions obtained by Illinois residents per 1000 reproductive age Illinois residents) and the non‐resident abortion rate (abortions ...
Erica S. Bishop +2 more
wiley +1 more source
Development of specific glucocorticoid receptor antagonists
European Journal of Psychotraumatology, 2012 Background / Methods : Mifepristone, a potent glucocorticoid receptor (GR) and progesterone receptor (PR) antagonist, has recently become the first medication approved for the treatment of Cushing's syndrome, the archetypal illness of cortisol ...
Joseph K. Belanoff
doaj +1 more source
Fertility & Reproduction, 2022 Background: Worldwide, millions of women seek treatment for early pregnancy loss (EPL) annually. Medical management with misoprostol is widely used, but only effective 60% of the time.
Charlotte HAMEL +15 more
doaj +1 more source
Prescribing Caution: A Critique of OpenEvidence to Answer Medication‐Related Questions
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 7, July 2026.ABSTRACT OpenEvidence is a newer medical large language model (LLM) that is growing in use among health professionals and students for clinical care and research. This paper provides an overview of existing literature on the accuracy of using OpenEvidence to answer clinical questions.
Jessica M. Bergsbaken +4 more
wiley +1 more source
The immunological effect of Galectin-9/TIM-3 pathway after low dose Mifepristone treatment in mice at 14.5 day of pregnancy. [PDF]
PLoS ONE, 2018 The abortifacient Mifepristone (RU486) has proven to be a safe, effective, acceptable option for millions of women seeking abortion during the first and second trimester of pregnancy although its precise mechanism of action is not well understood.
Adrienn Lajko +3 more
doaj +1 more source
Uterine Rupture Cases Over 15 Years in a District General Hospital: A Retrospective Case Series
Reproductive, Female and Child Health, Volume 5, Issue 2, June 2026.ABSTRACT Objective To evaluate the incidence, clinical presentation, management, and maternal and neonatal outcomes of uterine rupture over a 15‐year period in a UK district general hospital, and to assess local practice against the Royal College of Obstetricians and Gynaecologists (RCOG) Green‐top Guideline No. 45.
Asmaa Badr, Alexa Vardy
wiley +1 more source