Results 71 to 80 of about 4,386 (137)
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang +4 more
wiley +1 more source
Background Endometrial injury is a common disease in women caused by intrauterine inflammation, infections, and endocrine disorders. Human endometrial stromal cells (hEndoSCs) can maintain endometrial homeostasis and play an important role in repairing ...
Aibing Zhu, Fei Yao, Mingkun Shen
doaj +1 more source
Xylopia aethiopica fruit extract modulates progesterone and estradiol levels in monosodium glutamate‐induced uterine fibroid models. In silico analyses reveal strong binding of its phytochemicals to progesterone, estrogen, VEGFR2, and TGF‐β receptors, indicating multi‐target anti‐fibroid actions involving hormonal regulation, anti‐angiogenesis, and ...
Adedokun Oluwasegun +7 more
wiley +1 more source
Ferroptosis: Newly Emerged Regulator for Human Disease
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao +4 more
wiley +1 more source
Mifepristone Improves Octreotide Efficacy in Resistant Ectopic Cushing’s Syndrome
A 30-year-old Caucasian man presented with severe Cushing’s syndrome (CS) resulting from ectopic adrenocorticotropin syndrome (EAS) from a metastatic pancreatic neuroendocrine tumor.
Andreas G. Moraitis, Richard J. Auchus
doaj +1 more source
ALTERNATIVE APPROACHES TO MEDICAL ABORTION [PDF]
Medical abortion involving various pharmacological agents has demonstrated high levels of complete uterine evacuation. Alternative approaches involving letrozole, mifepristone, methotrexate used synergically with misoprostol are non-invasive elective ...
K. Telbiyska, M. Angelova
doaj +1 more source
Glioblastoma, the most common primary central nervous system tumor, is characterized by extensive vascular neoformation and an area of necrosis generated by rapid proliferation.
Monserrat Llaguno-Munive +7 more
doaj +1 more source
Incidence and preventability of severe early pregnancy morbidity at a tertiary referral center
Abstract Objectives To identify the incidence of severe early pregnancy morbidity (SEPM) by adapting severe maternal morbidity (SMM) definitions to pregnancies <24 weeks; secondarily, to assess preventability of these events using a validated tool Methods This is a retrospective cohort study of pregnant patients at a single tertiary care institution ...
Susan E. Nourse +7 more
wiley +1 more source
Reproductive outcomes following surgical removal of uterine fibroids
The cohort prospective comparative study investigated the efficacy of mifepristone use in patients after surgical treatment of uterine myoma. It was shown that the use of mifepristone at a dose of 50 mg/day in a continuous mode for 3 months after ...
A. E. Mitichkin +7 more
doaj +1 more source
Mifepristone: an alternate to dinoprostone in induction of labour [PDF]
Background: To assess and compare the efficacy, safety and fetomaternal outcome of mifepristone versus dinoprostone in priming the cervix and in inducing labour in pregnant women at term.Methods: This is a prospective comparative study done in Chettinad ...
Sailatha R. +11 more
core +1 more source

