Results 61 to 70 of about 17,319 (251)

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Mifepristone in the central nucleus of the amygdala reduces yohimbine stress-induced reinstatement of ethanol-seeking

, 2011
Chronic ethanol exposure leads to dysregulation of the hypothalamic-pituitary-adrenal axis, leading to changes in glucocorticoid release and function that have been proposed to maintain pathological alcohol consumption and increase vulnerability to ...
Simms, Jeffrey A, Selena E Bartlett, Bartlett, Selena E., Jeffrey A Simms, Haass-Koffler, Carolina L, Li, Rui, Rui Li, Jade Bito-Onon, Bito-Onon, Jade, Carolina L Haass-Koffler   +9 more
core   +1 more source

Mifepristone With Buccal Misoprostol for Medical Abortion [PDF]

, 2015
ObjectiveTo summarize clinical outcomes and adverse effects of medical abortion regimens consisting of mifepristone followed by buccal misoprostol in pregnancies through 70 days of gestation.Data sourcesWe used PubMed, ClinicalTrials.gov, and reference ...
Creinin, Mitchell D, Chen, Melissa J
core   +1 more source

Effects of mifepristone on adipocyte differentiation in mouse 3T3-L1 cells

Cellular & Molecular Biology Letters
Background Both glucocorticoid receptor and peroxisome proliferator-activated receptor-γ (PPARγ) play a critical role in adipocyte differentiation.
Takeshi Hashimoto, Katsuya Hirano
doaj   +1 more source

Mifepristone followed by misoprostol compared with placebo followed by misoprostol as medical treatment for early pregnancy loss (the Triple M trial): A double-blind placebo-controlled randomised trial

EClinicalMedicine, 2021
Background: Worldwide, millions of women seek treatment for early pregnancy loss (EPL) annually. Medical management with misoprostol is widely used, but only effective 60% of the time.
Charlotte Hamel, Sjors Coppus, Joyce van den Berg, Esther Hink, Jacoba van Seeters, Paul van Kesteren, Ashley Merién, Bas Torrenga, Rafli van de Laar, Josien Terwisscha van Scheltinga, Ingrid Gaugler-Senden, Peppino Graziosi, Minouche van Rumste, Ewka Nelissen, Frank Vandenbussche, Marcus Snijders   +15 more
doaj   +1 more source

Mifepristone: A potential postcoital contraceptive

, 2001
Mifepristone is an orally-active progesterone receptor antagonist. When a single dose of mifepristone is given in the mid- or late follicular phase, it may diminish or inhibit the luteinising hormone (LH) surge.
Ho, PC
core   +1 more source

Randomly Albright: The End of Judge Shopping in the Western District of Texas?

Journal of Empirical Legal Studies, EarlyView.
ABSTRACT Because judges exercise discretion in how they handle and decide cases, heterogeneity across judges can affect case outcomes and, thus, preferences among litigants for particular judges. However, selection obscures the causal mechanisms that drive these preferences.
Christian Helmers, Bernhard Ganglmair, Brian J. Love   +2 more
wiley   +1 more source

Mifepristone: Contraceptive and non-contraceptive uses

, 2002
Mifepristone is an orally active progesterone antagonist. It can be used for both contraceptive and non-contraceptive clinical indications. It is a very effective drug for emergency contraception with a low incidence of side effects. There is a potential
Pak, CH, Oi, ST, Ng, EHY
core   +1 more source

Rethinking Reproductive Governance: What Can Public Administration on the Island of Ireland Learn From Abortion Accompaniment?

Public Administration, EarlyView.
ABSTRACT The recent decriminalization of abortion marked a crucial step toward improved reproductive care on the island of Ireland. However, this has not translated into fully accessible abortion provision—barriers, including inaccessible services, persist, leaving gaps that public administration has not formally addressed. In response, informal actors,
Anna Theresa Schmid
wiley   +1 more source

British Abortion Law: Speaking from the Past to Govern the Future [PDF]

, 2016
This paper analyses the poor alignment of the aging statutory framework and modern understandings of medical best practice in the context of abortion services.
Sheldon, S., Sheldon, Sally
core   +1 more source