Results 41 to 50 of about 29,702 (243)

The regulatory cliff edge between contraception and abortion: the legal and moral significance of implantation [PDF]

, 2015
In regulating the voluntary interruption of pregnancy, English law has accorded particular significance to two biological events. First, ‘viability’, the moment when a fetus is said to acquire the capacity for independent life, plays an important role in
Campbell, Dickens, Goldthorp, Hursthouse, Husak, Keown, Lie, Noe, Packer, Potts, Prescription Only Medicines (Human Use) Order, Raymond, Sally Sheldon, Steinbock, Swahn, Taylor, Tunkel, Tunkel, Wilcox, Wilcox, Williams   +20 more
core   +5 more sources

How did the introduction of mifepristone impact the availability of abortion care in Ottawa? A qualitative study with abortion patients

FACETS, 2020
In 2017, mifepristone and misoprostol became available for early pregnancy termination as the combination pack Mifegymiso® in Ottawa, Ontario, Canada.
Kathryn J. LaRoche, Isabelle N. Labeca-Gordon, Angel M. Foster   +2 more
doaj   +1 more source

Glucocorticoid receptor expression in 20 solid tumor types using immunohistochemistry assay. [PDF]

, 2017
BackgroundGlucocorticoid receptor (GR) activity plays a role in many aspects of human physiology and may play a crucial role in chemotherapy resistance in a wide variety of solid tumors.
Block, Thaddeus S, Lynch, Frank J, Munster, Pamela N, Murphy, Tiffany I, Nguyen, Dat P   +4 more
core   +2 more sources

Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]

, 2015
A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding, Eugene Akujuru, Feliciano Protasi, Gabriel Mutungi, Goldberg AL, Lewis Arthurton, Simona Boncompagni, Timothy Pearson, Wing SS   +8 more
core   +1 more source

Medical termination for pregnancy in early first trimester (≤ 63 days) using combination of mifepristone and misoprostol or misoprostol alone: a systematic review

BMC Women's Health, 2020
Background A wide range of drugs have been studied for first trimester medical abortion. Studies evaluating different regimens, including combination mifepristone and misoprostol and misoprostol alone regimens, show varying results related to safety ...
F. A. Abubeker, Antonella F. Lavelanet, Maria I. Rodriguez, Caron R Kim   +3 more
semanticscholar   +1 more source

Cocktail treatment by GnRH-antagonist, letrozole, and mifepristone for the prevention of ovarian hyperstimulation syndrome: a prospective randomized trial

Gynecological Endocrinology, 2023
Objective This study is aimed to determine the efficacy of a cocktail style treatment by combining GnRH-antagonist, letrozole, and mifepristone on the prevention of ovarian hyperstimulation syndrome (OHSS) in high-risk women.Methods This prospective ...
Qianrong Qi, Yi Xia, Jin Luo, Yaqin Wang, Qingzhen Xie   +4 more
doaj   +1 more source

Mifepristone Antagonization With Progesterone to Prevent Medical Abortion: A Randomized Controlled Trial. [PDF]

, 2020
ObjectiveTo estimate the efficacy and safety of mifepristone antagonization with high-dose oral progesterone.MethodsWe planned to enroll 40 patients in a double-blind, placebo-controlled, randomized trial.
Chen, Melissa J, Creinin, Mitchell D, Dalton, Laura, Hou, Melody Y, Steward, Rachel   +4 more
core   +1 more source

Exosomes Derived from Umbilical Cord Mesenchymal Stem Cells Alleviate Mifepristone-Induced Human Endometrial Stromal Cell Injury

Stem Cells International, 2020
The human endometrial stromal cells (hEndoSCs) could maintain endometrial homeostasis and play a critical role in repairing endometrial injury. Mesenchymal stem cells (MSCs) significantly increase the proliferation of damaged hEndoSCs and protect them ...
Jianye Wang, Ruomeng Hu, Q. Xing, Xinghao Feng, Xiaohua Jiang, Yuping Xu, Zhaolian Wei   +6 more
semanticscholar   +1 more source

A screen of small molecule and genetic modulators of life span in female Drosophila identifies etomoxir, RH5849 and unanticipated temperature effects

Fly, 2022
Mifepristone increases life span in female Drosophila melanogaster, and its molecular target(s) remain unclear. Here small molecule and genetic interventions were tested for ability to mimic mifepristone, or to decrease life span in a way that can be ...
Gary N. Landis, Sebastian Ko, Oscar Peng, Brett Bognar, Michael Khmelkov, Hans S. Bell, John Tower   +6 more
doaj   +1 more source

Mifepristone-Induced Hypothyroidism

Journal of Investigative Medicine High Impact Case Reports, 2023
Medications are known to affect the thyroid physiology and are a known cause of hypothyroidism. There is an ever-growing list of medications that affect the thyroid by 1 or more mechanisms.
Niketa Kalara MD, Alex Manzano MD
doaj   +1 more source