Results 41 to 50 of about 4,386 (137)

FIGO statement on emergency contraception

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Emergency contraception remains an essential component of comprehensive contraceptive care and reproductive autonomy. Despite being safe, highly effective, and associated with almost no absolute medical contraindications or age limits, emergency contraception is often underutilized due to systemic barriers, limited access, persistent ...
Mikaela Koch, Asha Kasliwal, James Kiarie, Nasser Elkholy, Azra Ahsan, Aparna Sridhar   +5 more
wiley   +1 more source

Cytostasis and morphological changes induced by mifepristone in human metastatic cancer cells involve cytoskeletal filamentous actin reorganization and impairment of cell adhesion dynamics

BMC Cancer, 2013
Background Changes in cell shape and plasticity in cytoskeletal dynamics are critically involved in cell adhesion, migration, invasion and the overall process of metastasis.
Brandhagen BreeAnn N, Tieszen Chelsea R, Ulmer Tara M, Tracy Maria S, Goyeneche Alicia A, Telleria Carlos M   +5 more
doaj   +1 more source

A single-day treatment with mifepristone is sufficient to normalize chronic glucocorticoid induced suppression of hippocampal cell proliferation. [PDF]

PLoS ONE, 2012
BACKGROUND: Chronic stress or prolonged administration of glucocorticoids suppresses proliferation and/or survival of newborn cells in adult rat dentate gyrus.
Pu Hu, Charlotte Oomen, Anne-Marie van Dam, Jordi Wester, Jiang-Ning Zhou, Marian Joëls, Paul J Lucassen   +6 more
doaj   +1 more source

Mifepristone binding site interactions.

, 2013
ancSR2 is shown in slate blue; mifepristone is shown in magenta (oxygens, red; nitrogens, blue). Residues within 4.2 Å of the ligand are shown. A. Site-one mifepristone interacts with both the monomer in the asymmetric unit as well as residues in a ...
Jennifer K. Colucci (119487), Eric A. Ortlund (119490)   +1 more
core   +1 more source

State Choices, Unequal Access: Policies Shaping Reproductive Health Care Across the United States

The Milbank Quarterly, EarlyView.
Policy Points State policies and programs play an outsized role in shaping availability and access to sexual and reproductive health services across the nation. This has a major impact on women's access to contraception, abortion, and maternity services.
ALINA SALGANICOFF, IVETTE GOMEZ, USHA RANJI   +2 more
wiley   +1 more source

Management of early pregnancy loss by reproductive endocrinologists: does access to mifepristone matter?

F&S Reports
Objective: To describe patterns and variations in the medical and procedural management of early pregnancy loss (EPL) among reproductive endocrinology and infertility specialists, with attention to mifepristone use. Design: Cross-sectional.
Zachary S. Anderson, M.D., Richard J. Paulson, M.D., Brian T. Nguyen, M.Sc., M.D.   +2 more
doaj   +1 more source

Psychological Stress Promotes Tumor Growth in Hepatocellular Carcinoma Models Through Myeloid Signaling

Cancer Science, EarlyView.
Psychological stress promotes hepatocellular carcinoma progression through coordinated regulation of macrophages and neutrophils. Noradrenaline activates ADRB2 signaling in intratumoral macrophages, leading to CXCL2 production and neutrophil recruitment.
Keita Ogawa, Takahiro Aoki, Tatsuya Kaneko, Hongxuan Wang, Daiki Shimizu, Daisuke Katsumi, Iori Kojima, Hidekazu Tanaka, Kiwamu Motoyoshi, Ko Ozaki, Katsuhiro Nishimura, Tomohisa Iinuma, Mariko Takami, Shinichiro Motohashi   +13 more
wiley   +1 more source

Effects of mifepristone on adipocyte differentiation in mouse 3T3-L1 cells

Cellular & Molecular Biology Letters
Background Both glucocorticoid receptor and peroxisome proliferator-activated receptor-γ (PPARγ) play a critical role in adipocyte differentiation.
Takeshi Hashimoto, Katsuya Hirano
doaj   +1 more source

Clinical Outcomes and Women's Experiences before and after the Introduction of Mifepristone into Second-Trimester Medical Abortion Services in South Africa. [PDF]

PLoS ONE, 2016
OBJECTIVE:To document clinical outcomes and women's experiences following the introduction of mifepristone into South African public sector second-trimester medical abortion services, and compare with historic cohorts receiving misoprostol-only.
Deborah Constant, Jane Harries, Thokozile Malaba, Landon Myer, Malika Patel, Gregory Petro, Daniel Grossman   +6 more
doaj   +1 more source

Mifepristone in the central nucleus of the amygdala reduces yohimbine stress-induced reinstatement of ethanol-seeking

, 2011
Chronic ethanol exposure leads to dysregulation of the hypothalamic-pituitary-adrenal axis, leading to changes in glucocorticoid release and function that have been proposed to maintain pathological alcohol consumption and increase vulnerability to ...
Simms, Jeffrey A, Selena E Bartlett, Bartlett, Selena E., Jeffrey A Simms, Haass-Koffler, Carolina L, Li, Rui, Rui Li, Jade Bito-Onon, Bito-Onon, Jade, Carolina L Haass-Koffler   +9 more
core   +1 more source