Results 31 to 40 of about 29,702 (243)

Mifepristone Repurposing in Treatment of High-Grade Gliomas

open access: yesFrontiers in Oncology, 2021
Glioma is the most common and aggressive primary tumor of the central nervous system. The standard treatment for malignant gliomas is surgery followed by chemoradiotherapy.
Monserrat Llaguno-Munive   +3 more
semanticscholar   +1 more source

Determination of Mifepristone (RU-486) and Its Metabolites in Maternal Blood Sample after Pharmacological Abortion

open access: yesMolecules, 2022
The aim of the study was the development and validation of the UHPLC-QqQ-MS/MS method for the determination of mifepristone in human blood as well as the identification and quantification of its metabolites after self-induced pharmacological abortion ...
Paweł Szpot   +3 more
doaj   +1 more source

Perspectives Among Canadian Physicians on Factors Influencing Implementation of Mifepristone Medical Abortion: A National Qualitative Study

open access: yesAnnals of Family Medicine, 2020
PURPOSE Access to family planning health services in Canada has been historically inadequate and inequitable. A potential solution appeared when Health Canada approved mifepristone, the gold standard for medical abortion, in July 2015.
S. Munro   +12 more
semanticscholar   +1 more source

Pharmacist direct dispensing of mifepristone for medication abortion in Canada: a survey of community pharmacists

open access: yesBMJ Open, 2022
Introduction Pharmacists were acknowledged as the most appropriate healthcare professional to dispense mifepristone for medication abortion shortly after the prescription therapy became available in January 2017 in Canada.Objective We aimed to identify ...
Wendy V Norman   +3 more
doaj   +1 more source

Mifepristone Treatment in Pregnant Murine Model Induced Mammary Gland Dysplasia and Postpartum Hypogalactia

open access: yesFrontiers in Cell and Developmental Biology, 2020
Mammary gland dysplasia and postpartum hypogalactia often occur in humans and in the livestock breeding industry. However, their underlying mechanisms are not clear yet.
Hongmei Zhu   +7 more
doaj   +1 more source

Quality of Medication Abortion Services From Pharmacies and Drugstores in Ethiopia: A Two-Stage Study. [PDF]

open access: yesBJOG
ABSTRACT Objective To assess the quality of medication abortion (MA) services provided in pharmacies and drugstores (‘pharmaceutical outlets’) in Ethiopia. Design A two‐stage cross‐sectional study. Setting Pharmaceutical outlets in Addis Ababa, Ethiopia.
Tufa T   +6 more
europepmc   +2 more sources

Optimized pharmacological control over the AAV-Gene-Switch vector for regulable gene therapy

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Gene therapy in its current design is an irreversible process. It cannot be stopped in case of unwanted side effects, nor can expression levels of therapeutics be adjusted to individual patient’s needs.
Shi Cheng   +4 more
doaj   +1 more source

Effects of Progesterone and Its Antagonist Mifepristone on Progesterone Receptor A Expression in Human Umbilical Vein Endothelial Cells [PDF]

open access: yes, 2009
Effects of female steroid hormones on endothelial cells are gaining increased importance due to several studies on the effects of hormonal treatment on cardiovascular risk.
Friese, Klaus   +6 more
core   +1 more source

Resistance to cisplatin and paclitaxel does not affect the sensitivity of human ovarian cancer cells to antiprogestin- induced cytotoxicity [PDF]

open access: yes, 2014
BACKGROUND: Antiprogestin compounds have been shown to be effective in blocking the growth of ovarian cancer cells of different genetic backgrounds.
Gamarra Luques, Carlos Diego   +3 more
core   +1 more source

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