Results 11 to 20 of about 4,386 (137)

Mifepristone versus placebo to treat uterine myoma: a double-blind, randomized clinical trial

International Journal of Women's Health, 2013
Josep Lluis Carbonell Esteve,1 Rita Acosta,2 Yasmirian Pérez,2 Barbara Rodriguez,2 Isabel Seigler,2 Carlos Sanchez,2 Giuseppe Tomasi3 1Mediterránea Médica Clinic, Valencia, Spain; 2Eusebio Hernández Gynecology and Obstetrics ...
Esteve Carbonell JL, Acosta R, Perez Y, Rodriguez B, Seigler I, Sanchez C, Tomasi G   +6 more
doaj   +1 more source

Use of mifepristone in preparation of uterine cervix for delivery

Медицинский совет, 2013
The effectiveness of mifepristone in the preparation of cervix uteri to delivery was evaluated. Data on pregnancy, delivery and perinatal outcomes in 120 women with full-term births was analyzed. Mifepristone was most efficient in patients with Bishop's
V. A. Petrukhin, T. S. Kovalenko, K. N. Akhvlediani, M. V. Kapustina, E. V. Magilevskaya   +4 more
doaj   +2 more sources

Mifepristone Directly Disrupts Mouse Embryonic Development in Terms of Cellular Proliferation and Maturation In Vitro

Toxics, 2021
Mifepristone (RU-486), a synthetic steroid with potent antiprogestogen and anti-glucocorticoid properties, has been widely used in clinical practice. Its effect on the endometrium, ovary, and fallopian tube has been well reported in many human and animal
Yu-Ting Su, Jia-Shing Chen, Yi-Ru Tsai, Kuo-Chung Lan, Cheng-Chun Wu, Fu-Jen Huang   +5 more
doaj   +1 more source

The effects of mifepristone on the structure of human decidua and chorion and Bax and Bcl-2 expression at early stage of pregnancy

BMC Pharmacology and Toxicology, 2022
Background As a progesterone receptor antagonist, mifepristone combined with misoprostol is widely used to terminate early pregnancy in clinical practice.
Fei Tian, Hua Han, Ligang Jia, Junqin Zhang, Zhaoping Chu, Jie Li, Yuan Zhang, Ping Yan   +7 more
doaj   +1 more source

Pharmacist direct dispensing of mifepristone for medication abortion in Canada: a survey of community pharmacists

BMJ Open, 2022
Introduction Pharmacists were acknowledged as the most appropriate healthcare professional to dispense mifepristone for medication abortion shortly after the prescription therapy became available in January 2017 in Canada.Objective We aimed to identify ...
Wendy V Norman, Sarah Munro, Judith A Soon, Enav Z Zusman   +3 more
doaj   +1 more source

Mifepristone inhibited tumor progression by disrupting the stability of PD-L1 by miR-127-3p/VAMP2 in ovarian cancer

Pakistan Journal of Pharmaceutical Sciences, 2022
To investigate the effect of mifepristone on PD-L1 through miR-127-3p/VAMP2 axis to inhibit the malignant biological behavior of ovarian cancer cells. Western blotting was used to detect the protein expression of VAMP2, PD-L1, CyclinD1, Cl-caspase-3 and ...
Yixiao Gu, Yiqing Zhang, Jieyu Liu
doaj   +1 more source

Mifepristone reduces insulin resistance in patient volunteers with adrenal incidentalomas that secrete low levels of cortisol : a pilot study [PDF]

, 2013
Background: Incidental adrenal masses are commonly detected during imaging for other pathologies. 10% of the elderly population has an ‘adrenal incidentaloma’, up to 20% of these show low-grade autonomous cortisol secretion and 60% of patients with ...
Rita Chadarevian, Eastell, R. (Richard), Richard J Ross, Richard Eastell (153287), Chadarevian, Rita, Debono, M., Newell-Price, John, Rita Chadarevian (399995), Richard J. Ross (399996), Richard Eastell, Randeva, Harpal S., Chadarevian, R., John Newell-Price (399997), Newell-Price, J., Ross, R.J., Miguel Debono (399994), Ross, Richard J. M., Miguel Debono, John Newell-Price, Eastell, R.   +19 more
core   +1 more source

Mifepristone Treatment in Pregnant Murine Model Induced Mammary Gland Dysplasia and Postpartum Hypogalactia

Frontiers in Cell and Developmental Biology, 2020
Mammary gland dysplasia and postpartum hypogalactia often occur in humans and in the livestock breeding industry. However, their underlying mechanisms are not clear yet.
Hongmei Zhu, Xuchen Jia, Mingli Ren, Liguo Yang, Jianguo Chen, Li Han, Yi Ding, Mingxing Ding   +7 more
doaj   +1 more source

Determination of Mifepristone (RU-486) and Its Metabolites in Maternal Blood Sample after Pharmacological Abortion

Molecules, 2022
The aim of the study was the development and validation of the UHPLC-QqQ-MS/MS method for the determination of mifepristone in human blood as well as the identification and quantification of its metabolites after self-induced pharmacological abortion ...
Paweł Szpot, Olga Wachełko, Tomasz Jurek, Marcin Zawadzki   +3 more
doaj   +1 more source

Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review. [PDF]

, 2011
OBJECTIVE: To compare medical abortion practised at home and in clinics in terms of effectiveness, safety and acceptability. METHODS: A systematic search for randomized controlled trials and prospective cohort studies comparing home-based and clinic ...
Free, Caroline, Caroline Free, Min Hae Park, Haleema Shakur, Shakur, Haleema, Thoai D Ngo, Park, Min Hae, Ngo, Thoai D   +7 more
core   +1 more source