Results 21 to 30 of about 29,702 (243)
Mifepristone increases the cytotoxicity of uterine natural killer cells by acting as a glucocorticoid antagonist via ERK activation. [PDF]
PLoS ONE, 2012 Mifepristone (RU486), a potent antagonist of progesterone and glucocorticoids, is involved in immune regulation. Our previous studies demonstrated that mifepristone directly augments the cytotoxicity of human uterine natural killer (uNK) cells.
Yuezhou Chen +4 more
doaj +1 more source
Journal of Medical Case Reports, 2023 Background Mifepristone, also known as RU-486, is an anti-progestational steroid with similar chemical structure to anabolic steroids. Given as a single dose in conjunction with misoprostol, mifepristone is used to induce medical abortion.
Taylor A. Ault +4 more
doaj +1 more source
Interstitial Ectopic Pregnancy: The Role of Mifepristone in the Medical Treatment
International Journal of Environmental Research and Public Health, 2021 Interstitial pregnancy is defined as the presence of a gestational sac in the most proximal section of the fallopian tube. Management of interstitial pregnancy remains a debated topic.
G. Stabile +6 more
semanticscholar +1 more source
Management of early pregnancy loss with mifepristone and misoprostol: clinical predictors of treatment success from a randomized trial. [PDF]
, 2020 BackgroundEarly pregnancy loss is a common event in the first trimester, occurring in 15%-20% of confirmed pregnancies. A common evidence-based medical regimen for early pregnancy loss uses misoprostol, a prostaglandin E1 analog, with a dosage of 800 μg,
Atrio, Jessica M +6 more
core +1 more source
Obstetrics and Gynecology, 2021 The sequential use of mifepristone and misoprostol for termination of pregnancy after fetal death between 14 and 28 weeks of gestation reduces time to delivery compared with misoprostol alone.
E. Allanson +7 more
semanticscholar +1 more source
Medication Abortion With Pharmacist Dispensing of Mifepristone
Obstetrics and Gynecology, 2021 Medication abortion with pharmacist-dispensed mifepristone is effective, with a low prevalence of adverse events, and patients are satisfied with the model of care.
D. Grossman +12 more
semanticscholar +1 more source
Contraception, 2021 OBJECTIVE Protocols including mifepristone are the most effective medication regimens for medication abortion and early pregnancy loss (EPL) management. Both can be safely and effectively offered in primary care settings. Despite mifepristone's excellent
S. Srinivasulu +5 more
semanticscholar +1 more source
Toxics, 2021 Mifepristone (RU-486), a synthetic steroid with potent antiprogestogen and anti-glucocorticoid properties, has been widely used in clinical practice. Its effect on the endometrium, ovary, and fallopian tube has been well reported in many human and animal
Yu-Ting Su +5 more
doaj +1 more source
Mifepristone improves adipose tissue insulin sensitivity in insulin resistant individuals.
Journal of Clinical Endocrinology and Metabolism, 2021 BACKGROUND Increased tissue cortisol availability has been implicated in abnormal glucose and fat metabolism in patients with obesity, metabolic syndrome, and type 2 diabetes (T2DM).
Sriram Gubbi +5 more
semanticscholar +1 more source
BMC Pharmacology and Toxicology, 2022 Background As a progesterone receptor antagonist, mifepristone combined with misoprostol is widely used to terminate early pregnancy in clinical practice.
Fei Tian +7 more
doaj +1 more source