Results 21 to 30 of about 12,152 (205)

tudor[1] and mifepristone COX-PHA. [PDF]

open access: yes, 2023
Mating and receipt of male Sex Peptide hormone cause increased egg laying, increased midgut size and decreased life span in female Drosophila. Feeding mated females with the synthetic steroid mifepristone decreases egg production, reduces midgut size ...
Hanmei Bao (14952858)   +8 more
core   +1 more source

Dhr96[1] and mifepristone COX-PHA. [PDF]

open access: yes, 2023
Mating and receipt of male Sex Peptide hormone cause increased egg laying, increased midgut size and decreased life span in female Drosophila. Feeding mated females with the synthetic steroid mifepristone decreases egg production, reduces midgut size ...
Hanmei Bao (14952858)   +8 more
core   +1 more source

Mifepristone reduces insulin resistance in patient volunteers with adrenal incidentalomas that secrete low levels of cortisol : a pilot study [PDF]

open access: yes, 2013
Background: Incidental adrenal masses are commonly detected during imaging for other pathologies. 10% of the elderly population has an ‘adrenal incidentaloma’, up to 20% of these show low-grade autonomous cortisol secretion and 60% of patients with ...
Rita Chadarevian   +19 more
core   +1 more source

Mifepristone Treatment in Pregnant Murine Model Induced Mammary Gland Dysplasia and Postpartum Hypogalactia

open access: yesFrontiers in Cell and Developmental Biology, 2020
Mammary gland dysplasia and postpartum hypogalactia often occur in humans and in the livestock breeding industry. However, their underlying mechanisms are not clear yet.
Hongmei Zhu   +7 more
doaj   +1 more source

Pharmacist direct dispensing of mifepristone for medication abortion in Canada: a survey of community pharmacists

open access: yesBMJ Open, 2022
Introduction Pharmacists were acknowledged as the most appropriate healthcare professional to dispense mifepristone for medication abortion shortly after the prescription therapy became available in January 2017 in Canada.Objective We aimed to identify ...
Wendy V Norman   +3 more
doaj   +1 more source

Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review. [PDF]

open access: yes, 2011
OBJECTIVE: To compare medical abortion practised at home and in clinics in terms of effectiveness, safety and acceptability. METHODS: A systematic search for randomized controlled trials and prospective cohort studies comparing home-based and clinic ...
Free, Caroline   +7 more
core   +1 more source

Mifepristone inhibited tumor progression by disrupting the stability of PD-L1 by miR-127-3p/VAMP2 in ovarian cancer

open access: yesPakistan Journal of Pharmaceutical Sciences, 2022
To investigate the effect of mifepristone on PD-L1 through miR-127-3p/VAMP2 axis to inhibit the malignant biological behavior of ovarian cancer cells. Western blotting was used to detect the protein expression of VAMP2, PD-L1, CyclinD1, Cl-caspase-3 and ...
Yixiao Gu, Yiqing Zhang, Jieyu Liu
doaj   +1 more source

Determination of Mifepristone (RU-486) and Its Metabolites in Maternal Blood Sample after Pharmacological Abortion

open access: yesMolecules, 2022
The aim of the study was the development and validation of the UHPLC-QqQ-MS/MS method for the determination of mifepristone in human blood as well as the identification and quantification of its metabolites after self-induced pharmacological abortion ...
Paweł Szpot   +3 more
doaj   +1 more source

Synergistic lethality of mifepristone and LY294002 in ovarian cancer cells [PDF]

open access: yes, 2013
We have previously shown that the antiprogestin and antiglucocorticoid mifepristone inhibits the growth of ovarian cancer cells. In this work, we hypothesized that cellular stress caused by mifepristone is limited to cytostasis and that cell killing is ...
Wempe, Stacy L.   +2 more
core   +1 more source

Optimized pharmacological control over the AAV-Gene-Switch vector for regulable gene therapy

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Gene therapy in its current design is an irreversible process. It cannot be stopped in case of unwanted side effects, nor can expression levels of therapeutics be adjusted to individual patient’s needs.
Shi Cheng   +4 more
doaj   +1 more source

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