Results 51 to 60 of about 17,319 (251)
Molecular Oncology, 2016 The synthetic steroid mifepristone blocks the growth of ovarian cancer cells, yet the mechanism driving such effect is not entirely understood. Unbiased genomic and proteomic screenings using ovarian cancer cell lines of different genetic backgrounds and
Lei Zhang +13 more
doaj +1 more source
Advanced Science, EarlyView.The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu +10 more
wiley +1 more source
Modern approaches to the pre-induction cervical ripening of mifepristone
Репродуктивная эндокринология, 2018 The article deals modern approaches used of mifepristone in order to prepare the cervix for delivery. The results of a study of 222 patients in the gestation period of 37–42 gestation weeks which given orally administered 200 mg of mifepristone at ...
О. В. Кравченко
doaj +1 more source
A single-day treatment with mifepristone is sufficient to normalize chronic glucocorticoid induced suppression of hippocampal cell proliferation. [PDF]
PLoS ONE, 2012 BACKGROUND: Chronic stress or prolonged administration of glucocorticoids suppresses proliferation and/or survival of newborn cells in adult rat dentate gyrus.
Pu Hu +6 more
doaj +1 more source
State Choices, Unequal Access: Policies Shaping Reproductive Health Care Across the United States
The Milbank Quarterly, EarlyView.Policy Points State policies and programs play an outsized role in shaping availability and access to sexual and reproductive health services across the nation. This has a major impact on women's access to contraception, abortion, and maternity services.
ALINA SALGANICOFF +2 more
wiley +1 more source
BMC Cancer, 2013 Background Changes in cell shape and plasticity in cytoskeletal dynamics are critically involved in cell adhesion, migration, invasion and the overall process of metastasis.
Brandhagen BreeAnn N +5 more
doaj +1 more source
Clinical Endocrinology, EarlyView.ABSTRACT Objective Evaluate the effects of osilodrostat short‐ and long‐term treatment on health‐related quality of life (HRQoL) in Cushing's disease. Design LINC 3 and LINC 4 studies (pooled analysis). Patients 185 patients (mean baseline total scores: Cushing's Quality of Life [CushingQoL], 44.0; Beck Depression Inventory II [BDI‐II], 15.6; EuroQol ...
John Newell‐Price +6 more
wiley +1 more source
F&S ReportsObjective: To describe patterns and variations in the medical and procedural management of early pregnancy loss (EPL) among reproductive endocrinology and infertility specialists, with attention to mifepristone use. Design: Cross-sectional.
Zachary S. Anderson, M.D. +2 more
doaj +1 more source
Clinical Outcomes and Women's Experiences before and after the Introduction of Mifepristone into Second-Trimester Medical Abortion Services in South Africa. [PDF]
PLoS ONE, 2016 OBJECTIVE:To document clinical outcomes and women's experiences following the introduction of mifepristone into South African public sector second-trimester medical abortion services, and compare with historic cohorts receiving misoprostol-only.
Deborah Constant +6 more
doaj +1 more source
Mifepristone binding site interactions.
, 2013 ancSR2 is shown in slate blue; mifepristone is shown in magenta (oxygens, red; nitrogens, blue). Residues within 4.2 Å of the ligand are shown. A. Site-one mifepristone interacts with both the monomer in the asymmetric unit as well as residues in a ...
Jennifer K. Colucci (119487) +1 more
core +1 more source