Results 71 to 80 of about 18,934 (225)
Abstract Objectives/Background There is growing evidence that migraine is associated with attentional abnormalities, both during and between attacks, potentially affecting the cognitive processing of sensory stimulation. However, the underlying neurophysiological mechanism remains poorly understood.
Rémy Masson +6 more
wiley +1 more source
Plain Language Summary Migraine with aura can mimic a stroke, making diagnosis difficult and sometimes leading to unnecessary treatment in the acute setting. We found that some patients with migraine with aura show characteristic changes on brain perfusion CT scans, particularly in men and those with speech symptoms, which can be better detected using ...
Lucía Gómez Martín de la Escalera +8 more
wiley +1 more source
Suzetrigine as a novel treatment for headache disorders: A case series
Abstract Suzetrigine is a selective voltage‐gated sodium channel blocker that was recently approved by the US Food and Drug Administration for the treatment of acute pain. We retrospectively evaluated the efficacy and tolerability of suzetrigine for the treatment of different headache disorders in patients refractory to standard treatments in an ...
Molly Fensterwald +15 more
wiley +1 more source
Relationship between primary restless legs syndrome and migraine with aura
In this study, the prevalence and characteristics of definite migraine in primary restless legs syndrome (pRLS) patients and matched control patients (CPs) were investigated.
Bilgehan Atılgan Acar +7 more
doaj +1 more source
Mechanisms of increased sensitivity to noise and light in migraine headache
To determine whether phonophobia is a manifestation of loudness recruitment, the hearing and auditory discomfort thresholds to an 8000 Hz tone were measured during the headache-free interval and again during an attack of migraine in 16 migraine sufferers.
Woodhouse, A., Drummond, P.D.
core
Percutaneous closure of patent foramen ovale in migraine with aura, a randomized controlled trial. [PDF]
AIMS Migraine with aura and patent foramen ovale (PFO) are associated. The Percutaneous Closure of PFO in Migraine with Aura (PRIMA) trial is a multicentre, randomized trial to investigate the effect of percutaneous PFO closure in patients refractory ...
Windecker, Stephan +15 more
core +1 more source
High‐altitude headache: Insights into pathophysiology and potential treatment implications
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla +3 more
wiley +1 more source
The headache and aura-inducing effects of sildenafil in patients with migraine with aura
Introduction: It has not been established if migraine headache and migraine aura share common pathophysiological mechanisms. Sildenafil, a phosphodiesterase-5 inhibitor, causes cGMP accumulation and provokes migraine-like headache in patients with ...
S Eddelien, Heidi +2 more
core +1 more source
Is migraine a common manifestation of CADASIL-Cons
Headaches and transient neurological symptoms that bear resemblances to clinical manifestations of migraine, especially migraine with aura, are common among patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and ...
Yen-Feng Wang
doaj +1 more source
Abstract A population pharmacokinetic (popPK) model was developed for ubrogepant using data from 10 Phase 1, 1 Phase 2, and 2 Phase 3 studies. The data were described by a 2‐compartment model with linear elimination and transit compartment absorption. Formulation, food intake, race, gender, and hepatic impairment had a statistically significant impact ...
Sven Stodtmann +3 more
wiley +1 more source

