Results 41 to 50 of about 66,422 (218)
Background Addressing tuberculosis (TB) among migrants from high-burden countries is important for the health of migrants and for public health in low-TB-burden countries.
Sangnim Lee +6 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Introduction The Middle East and North African (MENA) region is characterised by high and complex migration flows, yet little is known about the health of migrant populations, their levels of underimmunisation and access to healthcare provision. Data are
+58 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Digital Technologies and Refugees’ Social Inclusion: The Use of ICTs by NGOs
Numerous studies highlight the direct impact of digital technologies on migrants, shaping their decisions to migrate, their migration trajectories, and their experiences in their destination countries. This article contributes to this emerging literature
Giacomo Solano +3 more
doaj +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Introduction This systematic review investigates the burden, clinical outcomes and risk factors of neglected tropical diseases (NTDs) and malaria in the Middle East and North African region, highlighting the urgency and scope of these health challenges ...
Farah Seedat +10 more
doaj +1 more source
EQUINE-FACILITATED THERAPY IN TREATING AN ASYLUM SEEKER GIRL WITH POST-TRAUMATIC STRESS DISORDER: A CASE STUDY [PDF]
Previous studies exist in using equine-facilitated therapy (EFT) in treating post-traumatic stress disorder (PTSD), however, no studies among refugees or asylum seekers were found.
Anu E. Castaneda +3 more
doaj
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source

