Results 61 to 70 of about 67,215 (309)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

What do we have to know from migrants' past exposures to understand their health status? a life course approach

, 2011
Spallek J, Zeeb H, Razum O. What do we have to know from migrants' past exposures to understand their health status? a life course approach. Emerging Themes in Epidemiology.
Jacob Spallek, Hajo Zeeb, Razum, Oliver, Spallek Jacob, Razum Oliver, Oliver Razum, Spallek, Jacob, Zeeb Hajo, Zeeb, Hajo   +8 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Factors influencing the health-seeking behavior of Vietnamese migrants in Japan: a cross-sectional study on knowledge, attitudes, and practices towards tuberculosis

Tropical Medicine and Health
Background Addressing tuberculosis (TB) among migrants from high-burden countries is important for the health of migrants and for public health in low-TB-burden countries.
Sangnim Lee, Nhan Nguyen Huu Thanh, Yusuke Akutsu, Yoshihisa Shirayama, Pham Nguyen Quy, Jin Takasaki, Akihiro Ohkado   +6 more
doaj   +1 more source

Multi-infection screening for migrant patients in UK primary care: Challenges and opportunities

Journal of Migration and Health
Background: Migrants in Europe face a disproportionate burden of undiagnosed infection, including tuberculosis, blood-borne viruses, and parasitic infections and many belong to an under-immunised group.
Jessica Carter, Felicity Knights, Anna Deal, Alison F Crawshaw, Sally E Hayward, Rebecca Hall, Philippa Matthews, Farah Seedat, Yusuf Ciftci, Dominik Zenner, Fatima Wurie, Ines Campos-Matos, Azeem Majeed, Ana Requena-Mendez, Sally Hargreaves   +14 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

UCL-Public-Health-Data-Science/CPRD-GOLD-migrant-phenotype-validation: Release v1.0.0 CPRD GOLD migrant phenotype metadata

, 2021
v1.0.0 codelists, code and ONS datasets used for the CPRD GOLD migrant phenotype ...
Claire Zhang
core   +1 more source

The burden, clinical outcomes and risk factors related to neglected tropical diseases and malaria in migrant populations in the Middle East and North Africa: a systematic review and meta-analyses

BMJ Global Health
Introduction This systematic review investigates the burden, clinical outcomes and risk factors of neglected tropical diseases (NTDs) and malaria in the Middle East and North African region, highlighting the urgency and scope of these health challenges ...
Farah Seedat, Sally Hargreaves, Ana Requena-Mendez, Helena Marti-Soler, Stella Evangelidou, Eman Elafef, Taha Maatoug, Ahmed Hamed Arisha, Mahmoud Hilali, Asad Adam, Ibrahim Bani   +10 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The health of migrants

Italian Journal of Medicine
Dear Editor,In Europe, more and more people of different nationalities are sharing spaces, services, and needs in a great mixture of traditions, habits, and languages...
Giuseppa Triolo, Cecilia Politi, Valeria Pignatelli   +2 more
openaire   +1 more source