Results 71 to 80 of about 11,978,086 (252)

Health-related quality of life in migrant preschool children [PDF]

, 2013
BACKGROUND: Minority groups have a lower health-related quality of life (HRQOL), but there is little information if this finding also applies to children. In this study, we compared HRQOL between young children with and without migrant parents.
Munsch, Simone, Pinto, A.M., Pinto, Ana Margarida, Munsch, S., Ana Margarida Pinto, Kriemler, S., Puder, J., Kriemler, Susi, Bonvin, A., Bodenman, Patrick, Susi Kriemler, Marques-Vidal, Pedro, Jardena Puder, Antoine Bonvin, Marques-Vidal, P., Puder, Jardena, Bonvin, Antoine, Bodenman, P., Simone Munsch, Patrick Bodenman, Pedro Marques-Vidal   +20 more
core   +2 more sources

Estimates of sexually transmitted infection prevalence and prevalence ratio among international migrants compared with non-migrants: A global systematic review and meta-analysis

International Journal of Infectious Diseases
Objectives: International migrants are disproportionately affected by HIV and blood-borne viruses compared with non-migrants in high-income countries, but data on prevalence and risk of other sexually transmitted infections (STIs) are scarce. We aimed to
Kathryn Mackey, Isra Al-Sharabi, Raphaela Berghammer-Bohmer, Beatriz Morais, Rubina Stanford Valodia, Sarah Tizzard, Philippe Mayaud, Sally Hargreaves, Julia M. Pescarini, Nuria Sanchez Clemente   +9 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Health equity and migrants in the Greater Mekong Subregion

Global Health Action, 2017
Background: Migrant health is receiving increasing international attention, reflecting recognition of the health inequities experienced among many migrant populations and the need for health systems to adapt to diverse migrant populations. In the Greater
Celia McMichael, Judith Healy
doaj   +1 more source

Determinants of internal migrant health and the healthy migrant effect in South India: a mixed methods study

BMC International Health and Human Rights, 2017
Background Internal labour migration is an important and necessary livelihood strategy for millions of individuals and households in India. However, the precarious position of migrant workers within Indian society may have consequences for the health of ...
Warren Dodd, Sally Humphries, Kirit Patel, Shannon Majowicz, Matthew Little, Cate Dewey   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

International migrant workers, heat exposure, and climate change: a systematic review of health risks and protective interventions

BMC Global and Public Health
Background International migrant workers, representing 170 million people globally, often face hazardous working conditions, including extreme heat exposure.
Lara Van der Horst, Oumnia Bouaddi, Sarah Williams, Meg Jago, Karen Lau, Ben Furber, Amirah Zafirah Zaini, Engy Mohamed El-Ghitany, Tharani Loganathan, Andreas D. Flouris, Davide J. Testa, Cathy Zimmerman, Sally Hargreaves, Consortium for Migrant Worker Health   +13 more
doaj   +1 more source

Migration, Urbanism and Health: Moving Toward Systems-Informed Policy and Practice [version 2; peer review: 1 approved, 2 approved with reservations]

F1000Research
Migration and displacement are pivotal determinants of urban health, influencing both direct and indirect health outcomes. Migrants may face unique health risks, often exacerbated by economic, social, and environmental factors encountered during transit ...
Karen Lau, Furio Honsell, Sally Hargreaves, Rita Sà Machado, Palmira Immordino, Cathy Zimmerman, Anna Ziersch, Yang Xiao, Irene Torres, Stefania Pascut   +9 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source