Results 31 to 40 of about 5,225,878 (289)

A foraging cost of migration for a partially migratory cyprinid fish. [PDF]

open access: yesPLoS ONE, 2013
Migration has evolved as a strategy to maximise individual fitness in response to seasonally changing ecological and environmental conditions. However, migration can also incur costs, and quantifying these costs can provide important clues to the ...
Ben B Chapman   +9 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Public opinion on migration [PDF]

open access: yes, 2018
Mapping and understanding what shapes public attitudes are particularly critical at a time when immigration is often perceived as one of the most important political issues facing countries around the world, with significant implications for election ...
DENNISON, James
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Research on switch migration method based on minimum cost path

open access: yesTongxin xuebao, 2020
In order to protect the controller,especially the controller in backbone network,from security threats and attacks,improve the security of the software-defined network (SDN) control plane,a switch migration algorithm based on minimum cost path was ...
Yingxu LAI, Yewei PU, Jing LIU
doaj   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Labour Migration for Vulnerable Communities: A Strategy to Adapt to a Changing Environment [PDF]

open access: yes, 2011
de Moor N. Labour Migration for Vulnerable Communities: A Strategy to Adapt to a Changing Environment. COMCAD Arbeitspapiere - Working Papers, 101.
Moor, Nicole de, de Moor, Nicole
core  

Evaluating cloud database migration options using workload models

open access: yesJournal of Cloud Computing: Advances, Systems and Applications, 2018
A key challenge in porting enterprise software systems to the cloud is the migration of their database. Choosing a cloud provider and service option (e.g., a database-as-a-service or a manually configured set of virtual machines) typically requires the ...
Martyn Ellison   +2 more
doaj   +1 more source

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