Results 41 to 50 of about 6,320,168 (363)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Research on switch migration method based on minimum cost path

open access: yesTongxin xuebao, 2020
In order to protect the controller,especially the controller in backbone network,from security threats and attacks,improve the security of the software-defined network (SDN) control plane,a switch migration algorithm based on minimum cost path was ...
Yingxu LAI, Yewei PU, Jing LIU
doaj   +2 more sources

Google Apps for Education: Valparaiso University\u27s Migration Experience [PDF]

open access: yes, 2012
Many campuses are investigating cloud-based or hosted email solutions. This paper will cover Valparaiso University’s decision to move to the Google Apps for Education platform and our campus migration strategy.
Klein, Rebecca   +2 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Research on dynamic migration of virtual machine based on security level

open access: yesTongxin xuebao, 2017
Side-channel attacks were the main ways of multi-tenant information leakage in the cloud computing and data center environments.The existing defense approaches based on dynamic migration of virtual machine have long convergence time of migration ...
Shuo ZHAO   +4 more
doaj   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

A multi-method approach to delineate and validate migratory corridors [PDF]

open access: yes, 2017
Context: Managers are faced with numerous methods for delineating wildlife movement corridors, and often must make decisions with limited data. Delineated corridors should be robust to different data and models.
Bond, Monica L.   +4 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Evaluating cloud database migration options using workload models

open access: yesJournal of Cloud Computing: Advances, Systems and Applications, 2018
A key challenge in porting enterprise software systems to the cloud is the migration of their database. Choosing a cloud provider and service option (e.g., a database-as-a-service or a manually configured set of virtual machines) typically requires the ...
Martyn Ellison   +2 more
doaj   +1 more source

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