Results 51 to 60 of about 6,320,168 (363)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Cost-aware live migration of services in the cloud [PDF]
Cloud computing is a paradigm in which dynamically scalable and often virtualized resources are provided as a service over the Internet. It is gaining popularity in a variety of domains such as web hosting, enterprise systems, and e-commerce sites.
David Breitgand, Gilad Kutiel, Danny Raz
openaire +2 more sources
Objective Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition with widely varying global prevalence estimates. The frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the United States or United Kingdom, at 19 to 39 per 100,000 as opposed ...
Lucinda Roper +7 more
wiley +1 more source
Cloud computing has been widely used in various industries in recent years. However, when migrating enterprise applications into the cloud, enterprise users face a problem with minimizing migration time and cloud resource providers face a dilemma of ...
Shiyong Li, Yue Zhang, Wei Sun
doaj +1 more source
AI-Empowered VNF Migration as a Cost-Loss-Effective Solution for Network Resilience [PDF]
Amina Lejla Ibrahimpasic +2 more
openalex +3 more sources
This study demonstrates an efficient recycling route for out‐of‐spec AlSi10Mg atomized powders through compaction and arc remelting followed by suction casting. By correlating compaction load, cooling rate, and resulting microstructure, we show that intermediate pressures (50–80 kN) and rapid cooling refine dendrites, reduce porosity, and enhance ...
Mila Christy de Oliveira +4 more
wiley +1 more source
High‐temperature interactions between low‐sulfur Al‐killed Mn–B steel and MgO–C refractories (0 and 50 wt% recyclates) are studied via finger immersion tests (1600 °C). Surface‐active elements influence infiltration. MgO/CaS layer forms, along with spinel and calcium silicate.
Matheus Roberto Bellé +5 more
wiley +1 more source
A Reliable and Efficient Data Migration Method Based On GlusterFS
Big data storage and high speed data access have become the main performance bottleneck for many big data applications. The higher speed data access and lower cost for storage must be required than some applications having small-scale data.
Li Li, Yin Gang, Wang Tao
doaj +1 more source

