Results 31 to 40 of about 10,089 (262)

Modelling Internal Migration with the Use of System Dynamics

open access: yesНаукові записки НаУКМА: Економічні науки, 2017
The article provides a detailed analysis of the theoretical basis for the study of labor migration, investigates the preconditions for interregional migration in Ukraine, identifies the effects of expulsion and attraction in different regions, and ...
Alina Novik
doaj   +1 more source

Each Step during Transendothelial Migration of Flowing Neutrophils is Regulated by the Stimulatory Concentration of Tumour Necrosis Factor-α [PDF]

open access: yesCell Adhesion and Communication, 1998
Migration of circulating neutrophils occurs in several steps: capture and rolling adhesion are followed by activation of beta 2-integrins and immobilisation, and then neutrophils move over and through the endothelium. However, it is not clear how the underlying mechanisms and completion of each step depend on the concentration of stimulatory cytokines ...
P, Bahra   +4 more
openaire   +2 more sources

Assessment of the experience of integration agreements of various types in the regulation of migration processes

open access: yesНаука. Культура. Общество, 2020
The article considers the classification of integration agreements in accordance with the approach to promoting labor mobility, formalizes the concepts of a “common” and “single” labor market.
Marina F. Tkachenko
doaj   +1 more source

Impact, regulation and health policy implications of physician migration in OECD countries

open access: yesHuman Resources for Health, 2004
Background In the face of rising demand for medical services due to ageing populations, physician migration flows are increasingly affecting the supply of physicians in Organisation for Economic Co-operation and development (OECD) countries.
Simoens Steven   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

2015 Migrant Crisis as a Stimulus for EU’s Modern Regulatory Policy Reconsidering: Management and Security Dimensions

open access: yesІсторико-політичні проблеми сучасного світу, 2017
The body of the article goes on to discuss the migration and refugee policy issues that went viral in media, as well as became widely discussed by experts and EU power-holding structures.
Volodymyr Fisanov
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Low Blood Flow After Angioplasty Augments Mechanisms of Restenosis [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2001
Abstract —The predominant cause of restenosis after angioplasty is now thought to be inward remodeling, but the mechanisms responsible are unknown. Remodeling in normal vessels is regulated by the endothelium in response to altered shear stress.
M R, Ward   +5 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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