Results 91 to 100 of about 2,446,659 (302)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Entrepreneurial Business and Economics Review, 2019 Objective: The study seeks to analyse the interaction of foreign direct investment, emigration, and immigration before and after the great economic recession.
Antonio Mihi-Ramirez +2 more
doaj +1 more source
Magnetite-based magnetoreception in birds: the effect of a biasing field and a pulse on migratory behavior [PDF]
, 2002 To test the hypothesis that single domain magnetite is involved in magnetoreception, we treated Australian silvereyes Zosterops l. lateralis with a strong, brief pulse designed to alter the magnetization of single domain particles.
Kirschvink, Joseph L. +3 more
core
Russian wheat aphids (Diuraphis noxia) in China: Native range expansion or recent introduction? [PDF]
, 2012 In this study, we explore the population genetics of the Russian wheat aphid (RWA) (Diuraphis noxia), one of the world’s most invasive agricultural pests, in north-western China.
Abbot +85 more
core +3 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Medicine Reports, 2014 Glucose-regulated protein 78 [GRP78, also termed binding immunoglobulin heavy chain protein (Bip)] may be involved in cancer progression and metastasis. However, to date there has been minimal investigation into its potential role in human prostate cancer cells.
Tong, Lu +11 more
openaire +3 more sources
Frontiers in Cellular Neuroscience, 2013 Neuronal progenitors capable of long distance migration are produced throughout life in the subventricular zone (SVZ). Migration from the SVZ is carried out along a well-defined pathway called the rostral migratory stream (RMS). Our recent finding of the
Åsa ePersson +2 more
doaj +1 more source
Factors affecting methylmercury biomagnification by a widespread aquatic invertebrate predator, the phantom midge larvae Chaoborus [PDF]
, 2012 MeHg biomagnification by the phantom midge Chaoborus in relation to MeHg concentrations in their prey and its migratory behavior was investigated in two Canadian Precambrian Shield lakes.
Aldamman, Lama +5 more
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source