Results 121 to 130 of about 2,446,659 (302)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Fluxos migratórios de mulheres para o trabalho reprodutivo: a globalização da assistência Migratory flows of women for reproductive work: the globalization of assistance

open access: yesRevista Estudos Feministas, 2007
A partir de uma experiência vivenciada como integrante do grupo que trabalhou a temática da migração de mulheres na Internationale Frauen Universität (IFU) em 2000, apresento neste artigo uma discussão sobre os fluxos migratórios de mulheres que deixam ...
Teresa Kleba Lisboa
doaj  

¿Donde esta el pollo? Cuba, sovranità alimentare e ontologia della scarsezza

open access: yesArchivio Antropologico Mediterraneo
Paradigms of sustainability are being formed in Cuba along autonomous paths, marked by the imposition of the bloqueo. The analysis focuses on changes rooted in the long-lasting crisis that followed the 1990s and on an 'ontology of scarcity', a ...
Elena Zapponi
doaj   +1 more source

Global Impacts Report 2017 [PDF]

open access: yes, 2017
Our fifth Global Impacts Report reflects on the progress of the MSC over the past 20 years, examines the sustainability performance of certified fisheries around the world and highlights areas of future ...
Catherine Longo   +2 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

International Guidelines for Securing Sustainable Small-scale Fisheries [PDF]

open access: yes, 2012
The 'Zero Draft' of the International Guidelines for Securing Sustainable Small-scale Fisheries(SSF Guidelines) has been prepared based on the outcomes of the extensive consultation process that has taken place during the last few years. This preliminary

core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

No. 27: Migration and Development in Contemporary Mauritius [PDF]

open access: yes, 2012
Mauritius is a society descended of involuntary and voluntary migrants. After two-and-a-half centuries of settlement as a plantation colony and by the time of its independence from colonial rule in 1968 the island nation’s population had grown to ...
Lincoln, David
core   +1 more source

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