Results 81 to 90 of about 17,026 (178)

Efficacy of a novel oral chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against natural flea and tick infestations on dogs presented as veterinary patients in Europe

Parasites & Vectors, 2020
Background A novel chewable oral tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) has recently been developed to provide persistent protection against flea and tick infections for a month, treatment of hookworm and roundworm ...
Csilla Becskei, Daphne Fias, Sean P. Mahabir, Robert Farkas   +3 more
doaj   +1 more source

A new β-class milbemycin derivative from a mutant of genetically engineered strain Streptomyces avermitilis AVE-H39

, 2021
A new β-class milbemycin, 13α-hydroxy milbemycin β6 (1), was isolated from the fermentation broth of a mutant of genetically engineered strain Streptomyces avermitilis AVE-H39.
Li-Qin Zhang (7599440), Shao-Yong Zhang (3222075), Wen-Shuai Song (11539360), Cheng-Hong Zhang (11539357), Wen-Sheng Xiang (544963), Ji-Dong Wang (544959), Huan Qi (424997)   +6 more
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Critically appraised topic for the most effective and safe treatment for canine generalised demodicosis

BMC Veterinary Research, 2019
Background Canine generalised demodicosis is an inflammatory parasitic skin disease caused by an excessive proliferation of Demodex spp. Generalized demodicosis is a severe skin disease, that can be life threatening if not treated properly.
Roberta Perego, Eva Spada, Caterina Foppa, Daniela Proverbio   +3 more
doaj   +1 more source

Trichophyton rubrum Azole Resistance Mediated by a New ABC Transporter, TruMDR3.

, 2019
The mechanisms of terbinafine resistance in a set of clinical isolates of Trichophyton rubrum have been studied recently. Of these isolates, TIMM20092 also showed reduced sensitivity to azoles.
Alshahni, M.M., Monod, M., Yamada, T., Salamin, K., Makimura, K., Fratti, M., Feuermann, M., Makino, M., Salamin K, Makimura K, Monod M, Yamada T, Makino M, Alshahni MM, Feuermann M, Fratti M, Mohamed Mahdi Alshahni, Maya Makino, Koichi Makimura, Tsuyoshi Yamada, Marina Fratti, Marc Feuermann, Karine Salamin, Michel Monod   +23 more
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Antimicrobial activities of macrocyclic lactones against M. ulcerans and M. marinum.

, 2015
aAbamectin, doramectin, emamectin, eprinomectin, ivermectin and selamectin are avermectins; moxidectin and milbemycin oxime are milbemycins.bThe resazurin and the MTT methods were used for M. ulcerans and M. marinum, respectively.Antimicrobial activities
Santiago Ramón-García (783176), Gerd Pluschke (7855), Charles J. Thompson (783175), Nicole Scherr (396149)   +3 more
core   +1 more source

Photochemical e-z isomerisation and cyclisation in an arylidenecycloakanone oxime ether system [PDF]

, 1994
The synthesis and photochemistry of a number of arylidenecycloalkanone oxime ethers has been investigated . Irradiation of E,E- 2-benzylidenecyclopentanone oxime O-allyl ether results in rapid E-Z isomérisation around the carbon-nitrogen double bond ...
Austin, Mark
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Efficacy of oral afoxolaner plus milbemycin oxime chewable (NexGard Spectra®, Merial) to prevent heartworm disease in dogs after inoculation with third stage larvae of Dirofilaria immitis

, 2015
The novel combination of afoxolaner plus milbemycin oxime, NexGard Spectra®, was evaluated against the migrating Dirofilaria immitis larvae in beagle dogs in two negative control, blinded laboratory studies. In each study, dogs were randomly allocated
Tielemans, Eric, Lebon, Wilfried, Larsen, Diane, Dumont, Pascal, GENCHI, Marco, Jeannin, Philippe   +5 more
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Pharmacokinetic meta-analysis summary of selected avermectins and milbemycins.

, 2015
aTheoretical AUC/MIC was calculated based on our in vitro MIC values of the avermectins against M. ulcerans. MIC values (in ng/mL) used for calculations were: ivermectin, 64,000; moxidectin, 32,000; milbemycin oxime, 2,000, and selamectin: 2,000 ...
Santiago Ramón-García (783176), Gerd Pluschke (7855), Charles J. Thompson (783175), Nicole Scherr (396149)   +3 more
core   +1 more source

Low Selectivity Indices of Ivermectin and Macrocyclic Lactones on SARS-CoV-2 Replication In Vitro

, 2022
Ivermectin was first approved for human use as an endectocide in the 1980s. It remains one of the most important global health medicines in history and has recently been shown to exert in vitro activity against SARS-CoV-2.
Sébastien Lyonnais, Alain Makinson, Merida, Peggy, Muriaux, Delphine, Swain, Jitendriya, Chable-Bessia, Christine, Neyret, Aymeric, Chesnais, Cédric, Hénaut, Mathilde, Gros, Nathalie, Nathalie Gros, Christine Chable-Bessia, Cédric Chesnais, Boullé, Charlotte, Lyonnais, Sébastien, Peggy Merida, Aymeric Neyret, Delphine Muriaux, Charlotte Boullé, Makinson, Alain, Jitendriya Swain, Mathilde Hénaut   +21 more
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THE EFFECTIVENES OF THE TWO ANTHELMINTICS PROGRAMS FOR THE GASTROINTESTINAL TRACT HELMINTS CONTROL FOR DOGS USING COMBIED ANTHELMINTICS (MILBEMYCIN OXIME/PRAZIQUANTEL) [PDF]

, 2014
In this study the effectiveness of two helmintic programs for the gastrointestinal helminthes control in dogs by using an combied anthelmintic (milbemycin oxime/praziquantel) was studied.
Puipaitė, Arneta
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