Results 91 to 100 of about 474,198 (345)

"I don't recognize myself" : personality characteristics in subjective cognitive impairment and mild cognitive impairment [PDF]

, 2013
Background: Personality changes are common in early stages of many neurodegenerative disorders and often precede cognitive deficits. In individuals with cognitive impairment an increase in feelings of distress and worry (neuroticism) and a decrease ...
Ausén, Birgitta
core   +1 more source

The Diverse Neuromuscular Spectrum of VPS13A Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger, Evamaria Riedel, Marie Hackenberg, Alexander Mensch, Stefanie Beck‐Woedl, Joohyun Park, Tobias B. Haack, Bernhard Haslinger, Jan Kirschke, Holger Prokisch, Andreas Hermann, Christian Mawrin, Adrian Danek, Benedikt Schoser, Kevin Peikert, Marcus Deschauer, Isabell Cordts   +16 more
wiley   +1 more source

Validation of Addenbrooke’s cognitive examination III for detecting mild cognitive impairment and dementia in Japan

BMC Geriatrics, 2019
Background Early detection of mild cognitive impairment (MCI) and dementia is very important to begin appropriate treatment promptly and to prevent disease exacerbation.
Shintaro Takenoshita, Seishi Terada, Hidenori Yoshida, Megumi Yamaguchi, Mayumi Yabe, Nao Imai, Makiko Horiuchi, Tomoko Miki, Osamu Yokota, Norihito Yamada   +9 more
doaj   +1 more source

Dementia and mild cognitive impairment in prisoners aged over 50 years in England and Wales: a mixed-methods study

Health Services and Delivery Research, 2020
Background: People aged ≥ 50 years constitute the fastest-growing group in the prison population of England and Wales. This population has complex health and social care needs.
Katrina Forsyth, Leanne Heathcote, Jane Senior, Baber Malik, Rachel Meacock, Katherine Perryman, Sue Tucker, Rachel Domone, Matthew Carr, Helen Hayes, Roger Webb, Laura Archer-Power, Alice Dawson, Sarah Leonard, David Challis, Stuart Ware, Richard Emsley, Caroline Sanders, Salman Karim, Seena Fazel, Adrian Hayes, Alistair Burns, Mary Piper, Jenny Shaw   +23 more
doaj   +1 more source

Comparison of the Quick Mild Cognitive Impairment (Qmci) screen to the Montreal Cognitive Assessment (MoCA) in an Australian geriatrics clinic [PDF]

, 2016
Introduction: The Montreal Cognitive Assessment (MoCA) accurately differentiates mild cognitive impairment (MCI) from mild dementia and normal controls (NC).
Albert, American Psychiatric Association, Bartlett, Bunt, Cooper, Dubois, Fiatarone Singh, Folstein, Freitas, Larner, Larner, Luis, Marc, Matthews, McKhann, McLennan, Metz, Mitchell, Molloy, Molloy, Molloy, Morris, Narazaki, Nasreddine, O'Caoimh, O'Caoimh, O'Caoimh, O'Caoimh, O'Caoimh, O'Caoimh, O'Caoimh, Petersen, Petersen, Plassman, Ritchie, Rossetti, Schafer, Standish, Tricco, Yesavage   +39 more
core   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source

Bibliometric analysis of research trends on factors affecting older adults with mild cognitive impairment

Frontiers in Neurology
BackgroundIn recent years, the problem of cognitive impairment in the elderly has become increasingly prominent. Understanding the research trend of influencing factors of mild cognitive impairment, and provide reference for medical staff to early ...
Lei Yang, Rushi Yang, Bo Wang, Tiantian Liu, Ziyi Wang   +4 more
doaj   +1 more source

MCI, en dan? De toekomst van 'mild cognitive impairment'

Tijdschrift voor Gerontologie en Geriatrie, 2014
Bespreking: Belleville, S., Gauthier, S., Lepage, E., Kergoat, M.J. & Gilbert, B. (2014). Predicting decline in mild cognitive impairment: a prospective cognitive study. Neuropsychology, 28, 643–652.
Han F.A. Diesfeldt
doaj   +1 more source

Improved Cardiorespiratory Fitness Is Associated with Increased Cortical Thickness in Mild Cognitive Impairment [PDF]

, 2015
Cortical atrophy is a biomarker of Alzheimer’s disease (AD) that correlates with clinical symptoms. This study examined changes in cortical thickness from before to after an exercise intervention in mild cognitive impairment (MCI) and healthy elders ...
Alfini, Alfonso J., Nielson, Kristy A., Reiter, Katherine, Smith, J. C., Smith, Theresa J., Weiss, Lauren R.   +5 more
core   +2 more sources

Nationwide Characterization of MFN2‐Related CMT in 176 Japanese Patients: Clinical and Genetic Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Mitofusin 2 (MFN2) is a major causative gene for axonal Charcot – Marie – Tooth disease type 2A (CMT2A), with a wide phenotypic spectrum. Comprehensive large ‐ scale genotype – phenotype association studies are essential for understanding disease pathogenesis and improved clinical management.
Masahiro Ando, Yujiro Higuchi, Jun‐Hui Yuan, Akiko Yoshimura, Chikashi Yano, Takahiro Hobara, Fumikazu Kojima, Yu Hiramatsu, Satoshi Nozuma, Tomonori Nakamura, Yusuke Sakiyama, Jun Mitsui, Shoji Tsuji, Hiroshi Takashima   +13 more
wiley   +1 more source