Results 181 to 190 of about 259,206 (307)

Premenopausal bilateral oophorectomy and Alzheimer's disease imaging biomarkers later in life

Alzheimer's &Dementia, EarlyView.
Abstract INTRODUCTION Premenopausal bilateral oophorectomy (PBO) before the age of 46 years is associated with an increased risk of dementia. We investigated the long‐term effects of PBO performed before age 50 years on amyloid beta (Aβ), tau, and neurodegeneration imaging biomarkers of Alzheimer's disease (AD).
Kejal Kantarci, Ekta Kapoor, Jennifer R. Geske, Anna Castillo, Julie A. Fields, Firat Kara, Evdokiya E. Knyazhanskaya, Christopher G. Schwarz, Matthew L. Senjem, Kent R. Bailey, Val Lowe, Nathan K. LeBrasseur, Walter A. Rocca, Michelle M. Mielke   +13 more
wiley   +1 more source

Prospects of genetic research of mild cognitive impairment [PDF]

, 2004
Cornelia M. van Duijn
openalex   +1 more source

Cognitive function in late‐stage HFpEF patients with tricuspid regurgitation undergoing transcatheter tricuspid valve intervention

Catheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1323-1330, December 1, 2022., 2022
Abstract Objectives This study evaluates the impact of transcatheter tricuspid valve interventions (TTVI) on cognitive function (CF), quality of life (QOL), and exercise capacity in late‐stage heart failure with preserved ejection fraction (HFpEF) and relevant tricuspid regurgitation (TR).
Muhammed Gerçek, Anca A. Irimie, Mustafa Gerçek, Henrik Fox, Vera Fortmeier, Tanja K. Rudolph, Volker Rudolph, Kai P. Friedrichs   +7 more
wiley   +1 more source

Regional brain volume changes in Hakim's disease versus Alzheimer's and mild cognitive impairment. [PDF]

Brain Commun
Yamada S, Yuzawa T, Ito H, Iseki C, Kondo T, Yamanaka T, Tanikawa M, Otani T, Ii S, Ohta Y, Watanabe Y, Wada S, Oshima M, Mase M.   +13 more
europepmc   +1 more source

Mild cognitive impairment: historical development and summary of research

, 2004
James Golomb, Alan Kluger, Steven H. Ferris   +2 more
openalex   +1 more source

Microglial ApoD‐induced NLRC4 inflammasome activation promotes Alzheimer's disease progression

Animal Models and Experimental Medicine, EarlyView.
We found that NLRC4 inflammasome was activated in microglia releasing IL6 and TNF‐α to impair the hippocampal neural stem cells (NSCs) self‐proliferation. ApoD contributed to activating NLRC4 inflammasome in microglia. Targeting the ApoD provides beneficial effects on NSCs self‐proliferation and mature neurons survival.
Yaliang Yu, Jianzhou Lv, Dan Ma, Ya Han, Yaheng Zhang, Shanlong Wang, Zhitao Wang   +6 more
wiley   +1 more source

Social cognition in mild cognitive impairment and dementia: A systematic review and meta-analysis. [PDF]

Alzheimers Dement
Shi P, Chapman H, Liu L, Rodgers F, Shaw J, Livingston G, Rankin KP, Warren JD, Sommerlad A.   +8 more
europepmc   +1 more source

Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment [PDF]

, 2005
Ronald Petersen, Ronald G. Thomas, Michael Grundman, David Bennett, Rachelle S. Doody, Steven H. Ferris, Douglas Galasko, Shelia Jin, Jeffrey Kaye, Allan I. Levey, Eric Pfeiffer, Mary Sano, Christopher H. van Dyck, Leon J. Thal   +13 more
openalex   +1 more source

Mild cognitive impairment: why bother?

Annals of General Psychiatry, 2008
Gold Gabriel
doaj   +1 more source

Neuroimaging Predictors of Cognitive Resilience against Alzheimer's Disease Pathology

Annals of Neurology, EarlyView.
Objective Some individuals demonstrate greater cognitive resilience—the ability to maintain cognitive performance despite adverse brain‐related changes—through as yet unknown mechanisms. We examined whether cortical thickness in several brain regions confers resilience against cognitive decline in amyloid‐positive adults by moderating the effects of ...
McKenna E. Williams, Christine Fennema‐Notestine, Tyler R. Bell, Shu‐Ju Lin, Stephen J. Glatt, William S. Kremen, Jeremy A. Elman, for the Alzheimer's Disease Neuroimaging Initiative   +7 more
wiley   +1 more source