Results 181 to 190 of about 792,865 (388)

Association between Oral Health and Mild Cognitive Impairment in Older Adults

Revista Cubana de Estomatología
Introduction: Along with the increase in the population of older adults, the prevalence of cognitive impairment is increasing. Recently, poor oral health has been introduced among potential risk factors.
Yordanis Garbey Pierre, Yudit Batista Delgado, Marlene Marina Gorguet Pi, Maria Eugenia Adjunta Medina   +3 more
doaj  

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Prediction of Progression in Patients with Mild Cognitive Impairment Using IMP-SPECT.

, 2000
Nobuyuki Okamura, Mitsutoshi Shinkawa, Hiroyuki Arai, Toshifumi Matsui, Kazushi Nakajo, Masahiro Maruyama, Xia Hu, Hidetada Sasaki   +7 more
openalex   +2 more sources

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

Advanced Science, EarlyView.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo, Qiancheng Mao, Xinyu Fang, Liuxuan Huang, Haoquan Tian, Wenguang Yang, Feiyue Zhou, Ke Ma   +7 more
wiley   +1 more source

Mild cognitive impairment: prevalence and incidence according to different diagnostic criteria: Results of the Leipzig Longitudinal Study of the Aged (LEILA75+) [PDF]

, 2003
Anja Busse, Jeannette Bischkopf, Steffi G. Riedel‐Heller, M C Angermeyer   +3 more
openalex   +1 more source

Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines

Movement Disorders, 2012
I. Litvan, J. Goldman, A. Tröster, B. Schmand, D. Weintraub, R. Petersen, B. Mollenhauer, C. Adler, K. Marder, C. Williams-Gray, D. Aarsland, J. Kulisevsky, M. Rodríguez-Oroz, D. Burn, R. Barker, M. Emre   +15 more
semanticscholar   +1 more source

Advanced Biomaterial Delivery of Hypoxia‐Conditioned Extracellular Vesicles (EVs) as a Therapeutic Platform for Traumatic Brain Injury

Advanced Science, EarlyView.
This research introduces a novel approach to enhance neuroregeneration following Traumatic Brain Injury (TBI). Extracellular Vesicles (EVs) are isolated from human neural progenitor cells under hypoxic conditions, leading to enhanced expression of neurogenic and angiogenic factors.
Joshua B. Stein, Songzi Zhang, Eun Ji Roh, Jeffrey Luo, Meizi Chen, Hyunjun Jang, Li Ling Goldston, Brandon Conklin, Inbo Han, Ki‐Bum Lee   +9 more
wiley   +1 more source

Mild Cognitive Impairment in the Population and Physical Health: Data on 1,435 Individuals Aged 75 to 95

, 2000
Giovanni B. Frisoni, Laura Fratiglioni, Johan Fastbom, Zhenyu Guo, Matti Viitanen, Bengt Winblad   +5 more
openalex   +1 more source

Biomarkers in Subjects with Amnestic Mild Cognitive Impairment [PDF]

, 2003
Masahiro Maruyama, Hiroyuki Arai, Mari Ootsuki, Nobuyuki Okamura, Toshifumi Matsui, Hidetada Sasaki, Tetsuro Yamazaki, Tomohiro Kaneta   +7 more
openalex   +1 more source

Igfbp2 Downregulation in PVT‐CeA Glutamatergic Circuits Drives Neonatal Anesthesia‐Induced Fear Memory Deficits

Advanced Science, EarlyView.
Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao, Ke Peng, Baojian Zhao, Xiaowen Meng, Gang Wang, Hanbing Xu, Li Deng, Xisheng Shan, Yichan Wang, Qiya Xu, Yanan Gao, Ruixia Weng, Hong Liu, Jin Tao, Huayue Liu, Shaoyong Song, Fuhai Ji   +16 more
wiley   +1 more source