Results 81 to 90 of about 307,888 (268)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Weighted pseudo-almost periodic solutions for some neutral partial functional differential equations

Electronic Journal of Differential Equations, 2012
In this article we study the existence of weighted pseudo almost periodic solutions of an autonomous neutral functional differential equation with Stepanov-Weighted pseudo almost periodic terms in a Banach space.
Mondher Damak, Khalil Ezzinbi, Lotfi Souden   +2 more
doaj  

Global Existence Results for Functional Differential Inclusions with State-Dependent Delay

Mathematical Modelling and Analysis, 2014
Our aim in this work is to study the existence of solutions of a functional differential inclusion with state-dependent delay. We use the Bohnenblust–Karlin fixed point theorem for the existence of solutions.
Mouffak Benchohra, Johnny Henderson, Imene Medjadj   +2 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Stochastic parabolic evolution equations in M-type 2 Banach spaces [PDF]

arXiv, 2015
This paper is devoted to studying stochastic parabolic evolution equations with additive noise in Banach spaces of M-type 2. We construct both strict and mild solutions possessing very strong regularities. First, we consider the linear case. We prove existence and uniqueness of strict and mild solutions and show their maximal regularities.
arxiv  

Remark on the uniqueness of the mild solution of SQG equation

Partial Differential Equations and Applications
We study the two-dimensional surface quasi-geostrophic equation. Motivated by the uniqueness for the three-dimensional incompressible Navier-Stokes equations, we demonstrate that the uniqueness of the mild solution of the two-dimensional surface quasi-geostrophic equation holds in the scaling critical Lebesgue space with a unique structure of the non ...
Iwabuchi, Tsukasa, Ueda, Ryoma
openaire   +2 more sources

On the existence of mild solutions of semilinear evolution differential inclusions

Journal of Mathematical Analysis and Applications, 2005
AbstractIn this paper we deal with a Cauchy problem governed by the following semilinear evolution differential inclusion: x′(t)∈A(t)x(t)+F(t,x(t)) and with initial data x(0)=x0∈E, where {A(t)}t∈[0,d] is a family of linear operators in the Banach space E generating an evolution operator and F is a Carathèodory type multifunction. We prove the existence
CARDINALI, Tiziana, RUBBIONI, Paola
openaire   +3 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Mild solution in the α-norm for some partial integrodifferential equations involving a nonlocal condition

Nonautonomous Dynamical Systems, 2023
In this work, we investigate the existence of mild solutions in the α\alpha -norm for a class of nonlocal integrodifferential equations. We employ the theory of resolvent operators introduced by R. Grimmer. The Leray-Schauder alternative is the principal
El Matloub Jaouad, Ezzinbi Khalil
doaj   +1 more source

On mild solutions of gradient systems in Hilbert spaces

Open Mathematics, 2013
Abstract We consider the Cauchy problem for an infinite-dimensional Ornstein-Uhlenbeck equation perturbed by gradient of a potential. We prove some results on existence and uniqueness of mild solutions of the problem. We also provide stochastic representation of mild solutions in terms of linear backward stochastic differential equations
openaire   +3 more sources