Results 151 to 160 of about 1,420,798 (364)

Lactococcus cremoris YRC3780 improves subjective stress response in the Uchida-Kraepelin test: a randomized, double-blind, placebo-controlled study

open access: yesScientific Reports
Lactococcus cremoris YRC3780, isolated from kefir, likely improves the hypothalamic–pituitary–adrenal axis response to acute psychological stress by acting on intestinal immune cells and promoting cytokine production.
Ikumi Fujioka, Kenji Uchida
doaj   +1 more source

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

open access: yesAdvanced Materials, EarlyView.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal   +9 more
wiley   +1 more source

An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide

open access: yesAdvanced Materials, EarlyView.
Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon   +5 more
wiley   +1 more source

Relationship between dietary protein intake and serum essential free amino acid concentrations in Japanese pregnant women: an observational study

open access: yesBMC Pregnancy and Childbirth
Background Insufficient protein intake decreases serum free amino acid (FAA) concentrations and worse whole-body nutritional status, leading to poor pregnancy outcomes.
Takuya Shibasaki   +9 more
doaj   +1 more source

Virus Enhanced Microrobots for Biofilm Eradication

open access: yesAdvanced Materials, EarlyView.
Biofilms resist antimicrobials across medicine, industry, and environments. We present virus‐conjugated microrobots synthesized hydrothermally and magnetically actuated. Their motion and viral specificity enable targeted binding, penetration, and delivery, outperforming bare microrobots.
Jyoti   +3 more
wiley   +1 more source

Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing

open access: yesAdvanced Materials, EarlyView.
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma   +9 more
wiley   +1 more source

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

open access: yesAdvanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba   +20 more
wiley   +1 more source

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