Results 51 to 60 of about 101,400 (303)

Development of a Sandwich ELISA to Measure Exposure to Occupational Cow Hair Allergens [PDF]

, 2011
Background: Cow hair and dander are important inducers of occupational allergies in cattle-exposed farmers. To estimate allergen exposure in farming environments, a sensitive enzyme immunoassay was developed to measure cow hair allergens.
Angelika Flagge, Anne Spickenheuer, Berger I, Christina Fleischer, Dennis Nowak, Eva Zahradnik, Ferrer A, Heutelbeck AR, Hinze S, Hinze S, Ilka Noss, Ingrid Sander, Joachim Sültz, Krakowiak A, Krop EJ, Lydia Bruckmaier, Monika Raulf-Heimsoth, Noss I, Noss I, Prahl P, Prahl P, Prahl P, Radon K, Rautiainen J, Rautiainen J, Renstrom A, Restani P, Rudolf Schierl, Saarelainen S, Thomas Brüning, Virtanen T, Virtanen T, Virtanen T, Ylonen J, Ylonen J, Ylonen J, Zahradnik E   +36 more
core   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Concentrations of Cysteinyl Leukotrienes in Various Biological Fluids of Children with Bronchial Asthma, Atopic Dermatitis and Food Protein Induced Enterocolitis [PDF]

, 2019
Clinical manifestation of food allergy is characterized by polymorphic cutaneous, respiratory and gastrointestinal syndromes. Leukotrienes occupy a key place in the pathogenesis of a wide range of inflammatory diseases, including bronchial asthma ...
Haiduchyk, H. (Halyna), Shadrin, O. (Oleg)   +1 more
core   +3 more sources

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Research progress of hydrolyzed milk protein on infant & toddlers’ health

Zhongguo shipin weisheng zazhi, 2022
Hydrolyzed milk proteins include hydrolyzed whey protein and hydrolyzed casein. Hydrolyzed whey protein can be divided into partial （moderate） hydrolyzed whey protein and extensive hydrolyzed whey protein.
ZHANG Yumei, MAO Shuai, TAN Shengjie, ZHANG Jian, SHI Yujie, LIU Biao   +5 more
doaj   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Studying informativity of specific IgE levels to whole cow milk allergen and its components, as well as to soy and gluten in children

Медицинская иммунология, 2022
Successive development of immunological tolerance to cow’s milk proteins largely depends on the timeliness and validity of the elimination diet and is most difficult in IgE-mediated food allergy.
N. A. Kovyazina, N. A. Alkhutova, A. V. Kamaev, O. V. Trusova, O. L. Zhizhina, M. O. Egorova   +5 more
doaj   +1 more source

Wine Fining with Plant Proteins [PDF]

, 2019
: Fining treatments involve the addition of a substance or a mixture to wine, and are generally carried out in order to clarify, stabilize or modify the wine\u2019s organoleptic characteristics. Usually these fining agents will bind the target compound(s)
Curioni, Andrea, Marangon, Matteo, Vincenzi, Simone   +2 more
core   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Cow’s milk protein allergy or lactose intolerance? Principles of differential diagnosis and diet therapy

Zdorovʹe Rebenka, 2019
Clinical gastrointestinal manifestations of cow’s milk protein allergy and lactase deficiency such as diarrhea, bloating, colic, and regurgitation are quite similar, which often lead to errors in diagnoses and methods of nutritional correction. Diagnoses
S.L. Nyankovskyy, О.S. Nyankovska, H.M. Trotskyy, N.V. Kamut   +3 more
doaj   +1 more source