Results 41 to 50 of about 32,048 (231)

IgE-mediated food allergies in Swiss infants and children

Swiss Medical Weekly, 2011
OBJECTIVE: To determine the most frequent food allergens causing immediate hypersensitivity reactions in Swiss children of different age groups and to investigate the clinical manifestation of IgE-mediated food allergies in young patients.
G Ferrari, PA Eng
doaj   +1 more source

Clinical Presentations of IgE-Mediated Cow’s Milk Allergy in Children and Factors Affecting the Development of Tolerance

Güncel Pediatri
Introduction: Food allergies are responses triggered by various immunological mechanisms to foods or additives, manifesting through IgE, non-IgE or mixed-type reactions.
Ughur Zeynallı, Muhammed Fatih Erbay, Şefika İlknur Kökçü Karadağ, Deniz Özçeker   +3 more
doaj   +1 more source

Eosinophilic colitis in infants

Jornal de Pediatria (Versão em Português), 2014
Objective: To review the literature for clinical data on infants with allergic or eosinophilic colitis. Data source: MEDLINE search of all indexes was performed using the words “colitis or procto-colitis and eosinophilic” or “colitis or proctocolitis and
Adriana Chebar Lozinsky, Mauro Batista de Morais   +1 more
doaj   +1 more source

Suckling by Schistosoma mansoni-infected mothers restored IgG2a and TGF-β production, but not IL-6 and delayed-type hypersensitivity in IL-12/IL-23-deficient mice

Revista da Sociedade Brasileira de Medicina Tropical, 2021
INTRODUCTION Suckling by schistosomotic mice improves anti-ovalbumin (OA) antibody production, while delayed-type hypersensitivity (DTH) remains unaffected.
Fabiana Leticia da Silva, Maria da Conceição Silva, Gabriela Calixto Ribeiro de Holanda, Eridan de Medeiros Coutinho, Silvia Maria Lucena Montenegro, Clarice Neuenschwander Lins de Morais, Valdênia Maria Oliveira de Souza   +6 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Health Related Quality of Life among schoolchildren aged 12–13 years in relation to food hypersensitivity phenotypes: a population-based study

Clinical and Translational Allergy, 2017
Background While Health Related Quality of Life has been investigated among children with IgE-mediated food allergy, less is known about quality of life among children with other types of hypersensitivity to food. The aim of this study was to investigate
Åsa Strinnholm, Linnéa Hedman, Anna Winberg, Sven-Arne Jansson, Viveca Lindh, Eva Rönmark   +5 more
doaj   +1 more source

Antigen-Specific Mammary Inflammation Depends on the Production of IL-17A and IFN-γ by Bovine CD4+ T Lymphocytes. [PDF]

PLoS ONE, 2015
Intramammary infusion of the antigen used to sensitize cows by the systemic route induces a local inflammation associated with neutrophil recruitment.
Pascal Rainard, Patricia Cunha, Marion Ledresseur, Christophe Staub, Jean-Luc Touzé, Florent Kempf, Florence B Gilbert, Gilles Foucras   +7 more
doaj   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

The prevalence of parent reported food hypersensitivity at school entry in Malta [PDF]

, 2020
Food hypersensitivity refers to an adverse reaction to food at a dose which is tolerated by the majority of individuals, which is further classified into allergic and non-allergic food-hypersensitivity.
Fallows, Stephen, Porter, Mariella
core  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source