Results 91 to 100 of about 7,235,853 (411)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Benzoic acid supplementation improves the growth performance, nutrient digestibility and nitrogen metabolism of weaned lambs

Frontiers in Veterinary Science
Nitrogen is one of the essential components of proteins and nucleic acids and plays a crucial role in the growth and development of ruminants. However, the nitrogen utilization rate of ruminants is lower than that of monogastric animals, which not only ...
Wenjie Zhang, Shuo Sun, Yaqian Zhang, Yanan Zhang, Jianguo Wang, Zhiqiang Liu, Kailun Yang   +6 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Veal calf industry economics [PDF]

, 2009
This paper provides an outline of the veal industry, its standing relative to other cattle farming enterprises, and its future prospects. In 2008 some 20 per cent of bovines slaughtered in the EU were for veal production and about one-third of them were
Fontguyon, Guy de, Sans, Pierre
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Reasons for developing or exiting business in the primary sector - A study of milk farmers in central-west Sweden [PDF]

The aim of this research was to study empirically what characterize farms and farmers that choose to develop the milk production at their farms. The background was that several farms have exited milk production, which threatens both goals about rural ...
Hansson, Helena, Johnsson, Viktor, Widnersson, Oskar   +2 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Influence of dietary supplementation of chromium on the carcass traits of crossbred pigs

Journal of Advanced Veterinary and Animal Research, 2014
This study was conducted to assess the influence of chromium on the carcass traits in crossbred (Large White Yorkshire X Landrace) pigs fed with swill feeding for a period of 5 months.
Guikinglung Pamei, P. Tensingh Gnanaraj, T. Sivakumar, K. Thilak Pon Jawahar, T. Muthuramalingam, P. Pothiappan   +5 more
doaj   +1 more source

Selected Results of the IFCN Dairy Network Milk Prices and Costs of Milk Production in 2003 [PDF]

Within the IFCN Dairy Network milk prices and costs of milk production have been analysed from 31 countries for the year 2003. A wide diversity of milk prices between the countries could be observed with > 35 US-$/100 kg milk in Switzerland, Norway and ...
Deeken, Eva, Hemme, Torsten
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source