Results 151 to 160 of about 273,070 (316)

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Association of Rumination Time with Metabolic Imbalance and Milk Quality Traits in Holstein Cattle. [PDF]

Biology (Basel)
Grigė S, Girdauskaitė A, Anskienė L, Sabeckienė I, Džermeikaitė K, Krištolaitytė J, Malašauskienė D, Televičius M, Antanaitis R.   +8 more
europepmc   +1 more source

THE QUANTITY AND QUALITY OF BREAST-MILK DURING THE FIRST TWO WEEKS OF THE PUERPERIUM. [PDF]

, 1908
EFFA V. DAVIS
openalex   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

Advanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye, Wen‐jing Luo, Lu Li, Wen‐di Shuai, Ling Zhou, You‐fa Duan, Xue Chen, Jun‐kai Zhang, Wenlin Huang, Ran‐yi Liu   +9 more
wiley   +1 more source

Climatic Variability and Milk Quality as Sustainability Indicators in Dairy Farming Systems of Pastaza Province, Ecuador. [PDF]

Animals (Basel)
Yanez Avalos D, de la Torres Moreira J, Delgado Lozada J, Villamarin Alvarez K, Montalvo Lozada M, Chuquimarca CC, Castillo Torres J, González-Puetate I, Mayorga Burbano R, Condo Plaza L, Paredes Orozco M, Marini P, Sánchez Pila F, Gallegos Guerra K.   +13 more
europepmc   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

<i>CSN1S1</i> and <i>CSN3</i> genetic variants affect milk quality traits in the buffalo population in Serbia. [PDF]

J Anim Sci Technol
Stepic S, Kuveljic J, Zivotic I, Perisic P, Bogdanovic V, Ignjatovic A, Zivkovic M.   +6 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Milk Quality Handbook. Practical Steps to Improve Milk Quality

, 2008
End of project report The overall objective of this booklet is to provide guidelines and recommendations for the on-farm milk production process such that the milk produced may achieve increasingly stringent milk hygiene and processing quality standards.
openaire   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source