ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu +12 more
wiley +1 more source
Exploring the dynamics of cow milk quality: A bibliometric and scoping review of dairy cattle research. [PDF]
Mulianda R +14 more
europepmc +1 more source
Management Practices of Bovine Mastitis and Milk Quality on Egyptian Dairies. [PDF]
Farag HS +7 more
europepmc +1 more source
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan +16 more
wiley +1 more source
Prevalence and Farm Management Factors and Milk Quality Changes Related to Bovine Mastitis in Small- and Medium-Sized Farms in the Central Highlands of Ecuador. [PDF]
Maya-Delgado A +9 more
europepmc +1 more source
A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su +10 more
wiley +1 more source
Effects of Adding Sodium Diacetate and <i>Aspergillus oryzae</i> to TMR Diets on Lactating Camel Production Performance, Milk Quality, and Fecal Microbiota. [PDF]
Wang Z +6 more
europepmc +1 more source
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang +17 more
wiley +1 more source
Purslane supplementation improved antioxidant capacity and milk quality potentially through rumen microbiota in dairy goats. [PDF]
Wang M +5 more
europepmc +1 more source

