Results 51 to 60 of about 14,372 (308)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Survey of biochemical and oxidative profile in donkey foals suckled with one natural and one semi-artificial technique. [PDF]

open access: yesPLoS ONE, 2018
Dairy donkey milking procedures require separating foals from their dams for a few hours a day. Artificial suckling in this species is a good technique for improving milk production and foal welfare.
Pasquale De Palo   +6 more
doaj   +1 more source

The nutrition and growth of lambs reared artificially with or without meal : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Animal Science at Massey University, Manawatu, New Zealand. [PDF]

open access: yes, 2017
Content removed from thesis due to copyright reasons: figure 1.1 (page 14). FAO (2011) Rearing young ruminants on milk replacers and starter feeds, Rome, FAO Animal Production and Health Manual No. 13. http://www.fao.org/docrep/014/i2439e/i2439e00.pdf ;
Jensen, Amber Celeste Myles
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

MILK REPLACER USE IN SUBSTITUTION OF WHOLE MILK ON THE PERFORMANCE OF HOLSTEIN CALVES DURING GROWING PHASE

open access: yesCiência Animal Brasileira, 2015
The objective of this study was to evaluate the biological efficiency of the milk replacer in the substitution of whole milk for calves at the first months of age and at rearing fase. This study was conducted in Universidade Tecnológica Federal do Paraná
Bruna Boito   +5 more
doaj  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Milk intake and carbon dioxide production of piglets determined with the doubly labelled water technique

open access: yesAnimal, 2007
The present study was undertaken to study different methodological aspects of quantifying CO2 production and milk intake of suckling piglets using the doubly labelled water (DLW) technique. In total, 37 piglets were enriched intraperitoneally with DLW to
P.K. Theil   +4 more
doaj   +1 more source

Feeding Techniques To Increase Calf Growth In The First Two Months Of Life [PDF]

open access: yes, 2008
End of project reportData from Cornell University and the University of Illinois in the USA suggested that average daily liveweight gains of 900 to 1000 g/calf/day could be achieved from birth to weaning provided the calf milk replacer (CMR) is ...
Dawson, L.   +3 more
core  

Developing the EU Farm Accountancy Data Network to derive indicators around the sustainable use of nitrogen and phosphorus at farm level. [PDF]

open access: yes, 2015
peer-reviewedThis study uses a national farm survey which is part of the European Union (EU) Farm Accountancy Data Network (FADN) to develop environmental sustainability indicators in the use of nitrogen (N) and phosphorus (P) across a range of farm ...
Buckley, Cathal   +3 more
core   +1 more source

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