Results 241 to 250 of about 714,375 (313)

NSUN5 Attenuates Renal Injury and Ferroptosis in Hyperuricaemic Nephropathy Through YBX2‐Dependent Stabilisation of SCD1 m5C Methylation

open access: yesAdvanced Science, EarlyView.
NSUN5 is downregulated in hyperuricaemic nephropathy. Overexpression of NSUN5 enhances the stability of SCD1 mRNA through the m5C reader YBX2, ultimately inhibiting ferroptosis in renal tubular epithelial cells. Additionally, this axis suppresses the NF‐κB signaling pathway to alleviate inflammation and upregulates ABCG2 to promote uric acid excretion,
Xiu‐xiu Song   +12 more
wiley   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

open access: yesAdvanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun   +15 more
wiley   +1 more source

Depletion of Amoxicillin and Its Major Metabolites in Anatolian Water Buffalo Milk After Intramuscular Administration. [PDF]

open access: yesAnimals (Basel)
Acaroz U   +6 more
europepmc   +1 more source

Microplastic contamination in commercial and traditional dairy products: occurrence, characteristics, and potential risk. [PDF]

open access: yesCurr Res Food Sci
Mitu SS   +12 more
europepmc   +1 more source

Adoption of food safety measures in smallholder dairy farms in Kenya: Implications for milk safety and public health. [PDF]

open access: yesOne Health
Nyokabi N   +7 more
europepmc   +1 more source

Microbiome of Bovine Milk and Factors Influencing Its Composition. [PDF]

open access: yesAnimals (Basel)
Szala Ł   +2 more
europepmc   +1 more source

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