The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source
Longitudinal Analysis of Physiological Adaptation in Primiparous Dairy Cows During the Transition Period. [PDF]
Girdauskaitė A +9 more
europepmc +1 more source
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang +8 more
wiley +1 more source
The Effect of Using Different Probiotics on the Performance, Digestibility of Nutrients, Feces Score, Blood Parameters and Skeletal Indices of Suckling Holstein's Calves. [PDF]
Hosseinabadi M +5 more
europepmc +1 more source
ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng +19 more
wiley +1 more source
Surface and Interfacial Engineering toward Durable Mechanically Coupled Flexible Electronics
This Review highlights how surface and interfacial engineering governs the reliability, durability, and functional stability of mechanically coupled flexible electronics. By integrating fundamental interfacial theory, failure mechanisms, multiscale engineering strategies, and representative applications, it provides a design‐oriented framework for ...
Qian Wang, Fangfang Dai, Wei Wu
wiley +1 more source
Development of a 3D-Printed Photometric Device for the Determination of Urea in Milk Samples. [PDF]
Dos Santos Trindade N +6 more
europepmc +1 more source
Bio‐Based Polyurethanes for Sustainable and Multifunctional Applications
Bio‐based polyurethanes prepared from vegetable oils, lignin, and polysaccharides have attracted increasing interest as alternatives to fossil‐derived polyurethanes. This review summarizes recent progress in their chemistry, structural engineering, and advanced applications, highlighting the roles of feedstocks, chain‐segment design, dynamic covalent ...
Xin Li +6 more
wiley +1 more source
Dairy Goats' Responses to Different Levels of Pomegranate By-Product Silage in the Diet: Productive Performance and Metabolic Indicators. [PDF]
Díaz JR +6 more
europepmc +1 more source
Abstract Producers in the Argentine Pampas often fail to fully replenish the nutrients extracted by crops, leading to unsustainable soil fertility management. The objectives of this study were to (i) evaluate grain yield, mineral nutrient concentration, and extraction for maize (Zea mays L.), wheat (Triticum aestivum L.), and soybean (Glycine max L ...
D. E. Becheran +4 more
wiley +1 more source

