Results 71 to 80 of about 1,355,564 (244)

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu   +10 more
wiley   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

open access: yesAdvanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang   +11 more
wiley   +1 more source

Digestible lysine levels in low-protein diets supplemented with synthetic amino acids for nursery, growing, and finishing barrows [PDF]

open access: yes, 2012
peer-reviewed articleTo investigate the effect of lysine level in low-protein diets (LPD) an experiment was conducted with 36 barrows fed 174, 140 and 118 g/kg of crude protein (CP), and three digestible lysine levels.
Sánchez-Torres, M. T.   +6 more
core   +1 more source

Voltamperometric Discrimination of Urea and Melamine Adulterated Skimmed Milk Powder

open access: yesSensors, 2012
Nitrogen compounds like urea and melamine are known to be commonly used for milk adulteration resulting in undesired intoxication; a well-known example is the Chinese episode occurred in 2008.
Eduardo Cortón   +4 more
doaj   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

open access: yesAdvanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang   +6 more
wiley   +1 more source

Study of coagulation properties of Holstein cow’s milk depending on the level of milk urea nitrogen in Macedonia dairy farms [PDF]

open access: yes, 2014
: In this paper an attempt has been made to obtain some investigations for coagulation properties of milk produced by Holstein-Friesian cows reared on local Pelagonia’s farms in the R. Macedonia.
Tomovska, Julijana   +3 more
core  

α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths

open access: yesAdvanced Science, EarlyView.
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel   +10 more
wiley   +1 more source

Physicochemical composition and fatty acid profile of milk from F1 Holstein x Zebu cows fed with increasing concentrations of urea

open access: yesSemina: Ciências Agrárias, 2015
We evaluated the physicochemical composition and fatty acid profile of milk from F1 Holstein × Zebu cows that were fed increasing levels of urea (0%, 33%, 66% and 100%, corresponding to 0%, 0.92%, 1.84% and 2.77% CP as NPN) as a substitute for soybean ...
Vanice Mendes de Souza   +7 more
doaj   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

open access: yesAdvanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan   +9 more
wiley   +1 more source

Effect of stocking management and nitrogen supplementation on pasture milk yield

open access: yesCiência Animal Brasileira, 2022
This study aimed to evaluate the effect of the first and last stocking strategies combined with a partial substitution of the protein from the supplement for urea nitrogen on nutrient intake and digestibility, milk composition, and nitrogen balance of ...
Rita Kelly Couto Brandão Dias   +8 more
doaj  

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