Results 81 to 90 of about 1,355,564 (244)

Pengaruh Suplementasi Baking Soda dalam Pakan terhadap Urea Darah dan Urea Susu Sapi Perah Laktasi

Jurnal Peternakan Indonesia, 2017
The aim of the research was to assess the effect of suplementation of sodium bicarbonate in feed rations on the concentration of Blood Urea Nitrogen (BUN) and Milk Urea Nitrogen (MUN) of lactating dairy cattle.
W. A. Harjanti, D. W. Harjanti, P. Sambodho , S. A. B. Santoso   +3 more
doaj   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

GWAS and genomic prediction of milk urea nitrogen in Australian and New Zealand dairy cattle. [PDF]

Genet Sel Evol, 2022
van den Berg I, Ho PN, Nguyen TV, Haile-Mariam M, MacLeod IM, Beatson PR, O'Connor E, Pryce JE.   +7 more
europepmc   +1 more source

AHR‐Responsive Carbon Dots Orchestrate Skin Wound Healing and Colonic Mucosal Repair via Treg‐Mediated Macrophage Efferocytosis

Advanced Science, EarlyView.
Guided by pharmacophore modeling and molecular docking, aryl hydrocarbon receptor (AHR)‐responsive carbon dots were synthesized. They bind directly to AHR and expand gut‐resident regulatory T (Treg) cells. Treg‐derived C‐C motif chemokine ligand 1 (CCL1) enhances macrophage efferocytosis, creating a pro‐regenetative niche that promotes colonic mucosal ...
Zilu Zhu, Han Zhang, Shuai Lin, Wenqian Zheng, Xin Li, Xiaowei Xu, Ruili Yang   +6 more
wiley   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

Advanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren, Qian Yue, Ning Gao, Qiu‐Lian Hao, Yan Huo, Chuchu Li, Xinyue Leng, Lu‐Lu Sun, Maggie Pui Man Hoi, Hai‐Hao Han, Mingliang Ma, Xu‐Wen Li   +11 more
wiley   +1 more source

Milk Urea Nitrogen and Infertility in Florida Dairy Cows

, 1999
While the negative impact of dietary protein on fertility in dairy cattle has been documented in several studies, the effect of urea nitrogen on fertility in dairy cattle in large dairy operations has not been fully investigated.
Donovan, Art, Melendez, Pedro, Hernandez, Jorge   +2 more
core   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

Soybean meal or cotton by-products associated with urea as source of nitrogen in the diet of lactating goats

Revista Brasileira de Zootecnia, 2013
The objective of this study was to evaluate the influence of sources of nitrogen on the intake and digestibility of nutrients and production and chemical composition of goat milk.
Aldivan Rodrigues Alves, Ariosvaldo Nunes de Medeiros, Juliana Silva de Oliveira, Roberto Germano Costa, Marcone Geraldo Costa, Rita de Cássia Ramos do Egypto Queiroga, Darklê Luiza de Souza   +6 more
doaj  

Effects of Milk Urea Nitrogen (MUN) and Climatological Factors on Reproduction Efficiency of Holstein Friesian and Jersey Cows in the Subtropics. [PDF]

Animals (Basel), 2021
Webb EC, de Bruyn E.
europepmc   +1 more source

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source