Results 41 to 50 of about 151,078 (334)

Candidate Members of the VMP/EMP Disk System of the Galaxy from the SkyMapper and SAGES Surveys

open access: yesThe Astrophysical Journal Supplement Series
Photometric stellar surveys now cover a large fraction of the sky, probe to fainter magnitudes than large-scale spectroscopic surveys, and are relatively free from the target selection biases often associated with such studies.
Jihye Hong   +17 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Additional Evidence for the Existence of a Primordial Disk System

open access: yesThe Astrophysical Journal
The origin of very metal-poor (VMP; [Fe/H] ≤ −2.0) stars on planar orbits has been the subject of great attention since their first discovery. However, prior to the release of the Gaia BP/RP (XP) spectra and large photometric samples such as SkyMapper ...
Shuai Xu   +9 more
doaj   +1 more source

Mapping the Milky Way Disk with Gaia DR3: 3D Extended Kinematic Maps and Rotation Curve to ≈30 kpc

open access: yesThe Astrophysical Journal, 2022
We apply a statistical deconvolution of the parallax errors based on Lucy’s inversion method (LIM) to the Gaia DR3 sources to measure their 3D velocity components in the range of Galactocentric distances R between 8 and 30 kpc with their corresponding ...
Hai-Feng Wang   +3 more
doaj   +1 more source

Chemodynamical simulations of the Milky Way galaxy [PDF]

open access: yes, 2011
We present chemodynamical simulations of a Milky-Way-type galaxy using a self-consistent hydrodynamical code that includes supernova feedback and chemical enrichment, and predict the spatial distribution of elements from oxygen to zinc.
Kobayashi, Chiaki, Nakasato, Naohito
core   +3 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Mass Models of the Milky Way and Estimation of Its Mass from the Gaia DR3 Data Set

open access: yesThe Astrophysical Journal, 2023
We use data from the Gaia DR3 data set to estimate the mass of the Milky Way (MW) by analyzing the rotation curve in the range of distances 5 to 28 kpc. We consider three mass models: The first model adds a spherical dark matter (DM) halo, following the ...
Francesco Sylos Labini   +3 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

The Milky Way’s Rowdy Neighbors: The Effects of the Large Magellanic Cloud and Sagittarius Dwarf on the Milky Way Disk

open access: yesThe Astrophysical Journal
The Milky Way (MW) is a barred spiral galaxy shaped by tidal interactions with its satellites. The Large Magellanic Cloud (LMC) and the Sagittarius dwarf galaxy (Sgr) are the dominant influences at the present day. This paper presents a suite of four 10 ^
Ioana A. Stelea   +2 more
doaj   +1 more source

Canals in Milky Way radio polarization maps [PDF]

open access: yes, 2006
Narrow depolarized canals are common in maps of the polarized synchrotron emission of the Milky Way. Two physical effects that can produce these canals have been identified: the presence of Faraday rotation measure ($\RM$) gradients in a foreground ...
Fletcher, Andrew, Shukurov, Anvar
core   +3 more sources

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