Results 61 to 70 of about 143,870 (318)
HALO7D. III. Chemical Abundances of Milky Way Halo Stars from Medium-resolution Spectra
The Halo Assembly in Lambda Cold Dark Matter: Observations in 7 Dimensions (HALO7D) survey measures the kinematics and chemical properties of stars in the Milky Way (MW) stellar halo to learn about the formation of our Galaxy.
Kevin A. McKinnon+6 more
doaj +1 more source
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu+11 more
wiley +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
On the nature of the Milky Way satellites [PDF]
18 pages, 16 figures.
Li Yang-Shyang+2 more
openaire +4 more sources
The search for metal-free stars has so far been unsuccessful, proving that if there are surviving stars from the first generation, they are rare, they have been polluted, or we have been looking in the wrong place.
Agarwal, Bhaskar+6 more
core +2 more sources
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Mapping the Chemodynamics of the Galactic Disk Using the LAMOST and APOGEE Red Clump Stars
A detailed measurement is made of the metallicity distributions, kinematics, and dynamics of the thin and thick disks across a large disk volume (5.0 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc) by using the LAMOST–APOGEE red clump stars.
Weixiang Sun+3 more
doaj +1 more source
All-sky Kinematics and Chemistry of Monoceros Stellar Overdensity
We explore the kinematic and chemical properties of the Monoceros stellar overdensity by combining data from the Two Micron All Sky Survey, Wide-field Infrared Survey Explorer, APOGEE, and Gaia.
Lais Borbolato+9 more
doaj +1 more source
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang+5 more
wiley +1 more source
We present a novel, deep-learning-based method—dubbed Galactic-Seismology Substructures and Streams Hunter, or GS ^3 Hunter for short—to search for substructures and streams in stellar kinematics data.
Guan-Yu Wang+6 more
doaj +1 more source