Results 81 to 90 of about 3,911 (275)

The Milky Way’s Rowdy Neighbors: The Effects of the Large Magellanic Cloud and Sagittarius Dwarf on the Milky Way Disk

The Astrophysical Journal
The Milky Way (MW) is a barred spiral galaxy shaped by tidal interactions with its satellites. The Large Magellanic Cloud (LMC) and the Sagittarius dwarf galaxy (Sgr) are the dominant influences at the present day. This paper presents a suite of four 10 ^
Ioana A. Stelea, Jason A. S. Hunt, Kathryn V. Johnston   +2 more
doaj   +1 more source

RBM12 Maintains Glioma Stem Cells by Activating Amino Acid‐Dependent mTORC1 Signaling via SLC7A5 mRNA Stabilization

Advanced Science, EarlyView.
This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei, Wenlong Luo, Shu Zhou, Lihao Wan, Peng Ling, Zhihua Huang, Zhihua Qian, Chenfei Lu, Mengyue Guo, Zhen Xue, Jun Qin, Ningwei Zhao, Jianghong Man, Wenchao Zhou, Zhiqiang Dong, Shutong Xu, Zhipeng Zhou, Xiuxing Wang, Weiwei Tao   +18 more
wiley   +1 more source

Characterizing circumstellar disk around young stars

, 2010
The circumstellar disks play a fundamental role in star and planet formation process. Studies on circumstellar disks are generally carried on following two viable approaches: "statistical" studies, where a large samples of sources are measured to ...
Schisano, Eugenio
core  

Substructure Depletion in the Milky Way Halo by the Disk

, 2019
We employ numerical simulations and simple analytical estimates to argue that dark matter substructures orbiting in the inner regions of the Galaxy can be efficiently destroyed by disk shocking, a dynamical process known to affect globular star clusters.
Keres, Dusan, Hernquist, Lars, Springel, Volker, D'Onghia, Elena   +3 more
core   +1 more source

Mapping the Chemodynamics of the Galactic Disk Using the LAMOST and APOGEE Red Clump Stars

The Astrophysical Journal Supplement Series
A detailed measurement is made of the metallicity distributions, kinematics, and dynamics of the thin and thick disks across a large disk volume (5.0 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc) by using the LAMOST–APOGEE red clump stars.
Weixiang Sun, Han Shen, Biwei Jiang, Xiaowei Liu   +3 more
doaj   +1 more source

Matrix Stiffness Induces Endothelial Network Senescence

Advanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song, Alexandra N. Rindone, Ya Guan, Connor D. Amelung, Prarthana Sanjay Daswani, Jennifer H. Elisseeff, Sharon Gerecht   +6 more
wiley   +1 more source

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

History of star formation and chemical enrichment in the Milky Way disk

, 2002
Based on a physical treatment of the star formation law similar to that given by Efstathiou, we have improved our two-component chemical evolution model for the Milky Way disk. Two gas infall rates are compared, one exponential, one Gaussian. It is shown
Shu, CG, Chang, RX, Hou, JL
core  

Signatures of a Tidally Induced Spiral Arm at the Anticenter of the Milky Way and a Kinematically Extended Anticenter Stream Using DESI Data Release 2

The Astronomical Journal
Using the Dark Energy Spectroscopic Instrument (DESI) Milky Way Survey, we examine the six-dimensional space of the anticenter region of the Milky Way stellar disk (150° < Galactic longitude < 220°) using 61,883 main-sequence turnoff stars.
Mika Lambert, Constance M. Rockosi, Sergey E. Koposov, Ting S. Li, Monica Valluri, Leandro Beraldo e Silva, Songting Li, João A. S. Amarante, Amanda Byström, Gustavo E. Medina, Nathan R. Sandford, Joan Najita, Namitha Kizhuprakkat, Jessica N. Aguilar, Steven Ahlen, Davide Bianchi, David Brooks, Todd Claybaugh, Kyle Dawson, Axel de la Macorra, Peter Doel, Jaime E. Forero-Romero, Enrique Gaztañaga, Satya Gontcho A Gontcho, Gaston Gutierrez, Richard Joyce, Anthony Kremin, Claire Lamman, Martin Landriau, Laurent Le Guillou, Marc Manera, Aaron Meisner, Ramon Miquel, John Moustakas, Adam Myers, Seshadri Nadathur, Will Percival, Francisco Prada, Ignasi Pérez-Ràfols, Graziano Rossi, Eusebio Sanchez, David Schlegel, Michael Schubnell, Joseph H. Silber, David Sprayberry, Gregory Tarlé, Benjamin A. Weaver, Rongpu Zhou, Hu Zou   +48 more
doaj   +1 more source

Disk Galaxy Evolution: From the Milky Way to High-Redshift Disks [PDF]

Astrophysics and Space Science, 2003
We develop a detailed model of the Milky Way (a ``prototypical'' disk galaxy) and extend it to other disks with the help of some simple scaling relations, obtained in the framework of Cold Dark Matter models. This phenomenological (``hybrid'') approach to the study of disk galaxy evolution allows us to reproduce successfully a large number of observed ...
openaire   +2 more sources