Results 71 to 80 of about 3,911 (275)

The Stellar Disk Structure Revealed by the Mono-age Populations of the LAMOST Red Clump Star Sample

open access: yesThe Astronomical Journal
Understanding the structure of the Galactic disk is crucial for understanding the formation and evolutionary history of the Milky Way. This study examines the structure of the Galactic disk by analyzing a sample of 138,667 primary red clump (RC) stars ...
Zheng Yu   +4 more
doaj   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

open access: yesAdvanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu   +11 more
wiley   +1 more source

An Inward-moving and Asymmetric Velocity Wave Detected in LAMOST-Gaia

open access: yesThe Astrophysical Journal Letters
The phase space, as coded by kinematic parameters and chemical abundances, is crucial for understanding the formation of the Galactic disk. Using red giant stars from the Galactic thin disk with [Fe/H] > − 0.8 and low- α ratios identified in LAMOST-Gaia,
Yuqin Chen   +5 more
doaj   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

open access: yesAdvanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg   +18 more
wiley   +1 more source

Icarus Revisited: An Ancient, Metal-poor Accreted Stellar Stream in the Disk of the Milky Way

open access: yesThe Astrophysical Journal
The search for accreted satellites in the Galactic disk is a challenging task, to which Gaia plays a crucial role in synergy with ground-based spectroscopic surveys. In 2021, P. Re Fiorentin et al.
Paola Re Fiorentin   +4 more
doaj   +1 more source

On the Formation of Planets in the Milky Way’s Thick Disk

open access: yesThe Astrophysical Journal
Abstract Exoplanet demographic surveys have revealed that close-in (≲1 au) small planets orbiting stars in the Milky Way’s thick disk are ∼50% less abundant than those orbiting stars in the Galactic thin disk. One key difference between the two stellar populations is the time at which they emerged: thick-disk stars are the likely product
Tim Hallatt, Eve J. Lee
openaire   +3 more sources

Riding the kinematic waves in the Milky Way disk with Gaia [PDF]

open access: yesAstronomy & Astrophysics, 2018
Context. Gaia DR2 has delivered full-sky six-dimensional measurements for millions of stars, and the quest to understand the dynamics of our Galaxy has entered a new phase. Aims. Our aim is to reveal and characterise the kinematic substructure of the different Galactic neighbourhoods, to form a picture of their spatial evolution that can be used to ...
Ramos, P., Antoja, T., Figueras, F.
openaire   +3 more sources

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

The Milky Way’s Circular Velocity Curve Measured Using Element Abundance Gradients

open access: yesThe Astrophysical Journal
Spectroscopic surveys now supply precise stellar label measurements such as element abundances for large samples of stars throughout the Milky Way. These element abundances are known to correlate with orbital actions or other dynamical invariants.
Danny Horta   +6 more
doaj   +1 more source

Pericentrosomal Redistribution of the Endoplasmic Reticulum Ensures Organelle Symmetric Inheritance and Mitotic Progression

open access: yesAdvanced Science, EarlyView.
Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu   +9 more
wiley   +1 more source

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