Results 71 to 80 of about 3,194 (299)

A Study of the Properties and Dynamics of the Disk of Satellites in a Milky-Way-like Galaxy System

, 2023
The dynamics of the satellite systems of Milky-Way-like galaxies offer a useful means by which to study the galaxy formation process in the cosmological context. It has been suggested that the currently observed anisotropic distribution of the satellites
Mathews, Grant J., Xinghai Zhao, Phillips, Lara Arielle, Zhao, Xinghai, Tang, Guobao, Guobao Tang, Grant J. Mathews, Lara Arielle Phillips   +7 more
core   +2 more sources

Dynamical Models of the Milky Way in Action Space with LAMOST DR8 and Gaia EDR3

The Astrophysical Journal
This work explores dynamical models of the Milky Way (MW) by analyzing a sample of 86,109 K giant stars selected through cross-matching the LAMOST DR8 and Gaia EDR3 surveys. Our earlier torus models of Q. Wang et al.
Guang-Chen Sun, Qiao Wang, Shude Mao, Yichao Li, Richard J. Long, Ping-Jie Ding, Yougang Wang, Xin Zhang, Xuelei Chen   +8 more
doaj   +1 more source

Stream Fanning and Bifurcations: Observable Signatures of Resonances in Stellar Stream Morphology

The Astrophysical Journal, 2023
Recent observations have revealed a trove of unexpected morphological features in many of the Milky Way’s stellar streams. Explanations for such features include time-dependent deformations of the Galactic gravitational potential, local disruptions ...
Tomer D. Yavetz, Kathryn V. Johnston, Sarah Pearson, Adrian M. Price-Whelan, Chris Hamilton   +4 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Orbital Torus Imaging: Acceleration, Density, and Dark Matter in the Galactic Disk Measured with Element Abundance Gradients

The Astrophysical Journal
Under the assumption of a simple and time-invariant gravitational potential, many Galactic dynamics techniques infer the milky Way’s mass and dark matter distributions from stellar kinematic observations.
Danny Horta, Adrian M. Price-Whelan, David W. Hogg, Kathryn V. Johnston, Lawrence Widrow, Julianne J. Dalcanton, Melissa K. Ness, Jason A. S. Hunt   +7 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Dynamics and history of the Milky Way with Gaia

, 2022
:  Thanks to the large amount of data delivered by the Gaia satellite and their excellent precision, in the last three years we have experienced a vertiginous progress in the studies of our Galaxy.
Antoja, Teresa
core  

The Milky Way’s Rowdy Neighbors: The Effects of the Large Magellanic Cloud and Sagittarius Dwarf on the Milky Way Disk

The Astrophysical Journal
The Milky Way (MW) is a barred spiral galaxy shaped by tidal interactions with its satellites. The Large Magellanic Cloud (LMC) and the Sagittarius dwarf galaxy (Sgr) are the dominant influences at the present day. This paper presents a suite of four 10 ^
Ioana A. Stelea, Jason A. S. Hunt, Kathryn V. Johnston   +2 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

On the Corotation of Milky Way Satellites: LMC-mass Satellites Induce Apparent Motions in Outer Halo Tracers

The Astrophysical Journal
Understanding the physical mechanism behind the formation of a corotating thin plane of satellite galaxies, like the one observed around the Milky Way (MW), has been challenging.
Nicolás Garavito-Camargo, Adrian M. Price-Whelan, Jenna Samuel, Emily C. Cunningham, Ekta Patel, Andrew Wetzel, Kathryn V. Johnston, Arpit Arora, Robyn E. Sanderson, Lehman Garrison, Danny Horta   +10 more
doaj   +1 more source